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Observation on the clinical efficacy of the classical formula Houpo-zhishi Tang combined with Bifico applied to diarrhea-type irritable bowel syndrome

Observation on the clinical efficacy of the classical formula Houpo-zhishi Tang combined with Bifico applied to diarrhea-type irritable bowel syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000780
Enrollment
Unknown
Registered
2025-04-17
Start date
2023-03-08
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irritable bowel syndrome

Interventions

Control Group:Bifico
Experimental Group:Bifico+modified Houpo Zhishi Decoction

Sponsors

Shanghai Seventh People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Meeting the diagnostic criteria for IBS-D classification as interpreted in the "Expert Consensus Opinion on Irritable Bowel Syndrome in China (2020)" and the diagnostic criteria for IBS-D with spleen deficiency syndrome in the "Expert Consensus Opinion on the Diagnosis and Treatment of Irritable Bowel Syndrome in Traditional Chinese Medicine (2017)". 2) Presenting clinical symptoms of IBS-D such as abdominal pain and discomfort during defecation. 3) Having complete clinical data. 4) Having no history of drug allergy.

Exclusion criteria

Exclusion criteria: 1) Mental disorders; 2) Severe organ diseases such as heart, liver and kidney; 3) Pregnant women; 4) Lactating women; 5) Coagulation disorders; 6) Immune system diseases.

Design outcomes

Primary

MeasureTime frame
IBS-SSS score;

Secondary

MeasureTime frame
Prealbumin(PA);Albumin(ALB);motilin(MTL);TCM symptom score;Gastrin(GAS);

Countries

China

Contacts

Public ContactYin benfan

Shanghai Seventh People's Hospital

286416207@qq.com18621053460

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026