heart failure
Conditions
Interventions
treatment group:The treatment group was combined with Yiqi Qiangxin decoction on the basis of control group
control group:Routine quadruple medication for heart failure
Sponsors
Dongzhimen Hospital of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the above diagnostic criteria of Western Medicine HFrEF (NYHA Grade ?-?) and Chinese medicine chronic heart failure syndrome of Qi deficiency and blood stasis; (2) Age 18-75 years old male or female; (3) Able to communicate orally and in writing; (4) Voluntarily participate in this study can obey the treatment plan and voluntarily sign the informed consent or the legal guardian informed consent and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of acute heart failure within the last 30 days; (2) The main right heart dysfunction; (3) Those who are unable to complete the relevant examination of this study due to activities inconvenience or other reasons; (4) Patients with a history of malignant tumor requiring regular radiotherapy and chemotherapy; (5) Patients with rheumatoid arthritis lupus erythematosus and other diseases who need to take immunosuppressants regularly; (6) Patients with abnormal liver function (ALT AST or ALP=3× upper limit of normal); (7) Patients with severe renal insufficiency (estimated glomerular filtration rate eGFR < 30) Estimated glomerular filtration rate eGFR < 30 ml/(min·1.73m2); (8) Obvious hemodynamic changes caused by left ventricular outflow tract obstruction aortic aneurysm aortic dissection or unrepaired valve; (9) Patients who are known to be allergic to the drugs or drug ingredients used in this study; (10) Women who are pregnant or planning to become pregnant and breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N-Terminal Pro-Brain Natriuretic Peptide; | — |
Secondary
| Measure | Time frame |
|---|---|
| ultrasonic cardiogram;cystatin C;New York Heart Association Functional Classification;Minnesota Living with Heart Failure Questionnaire;Major Adverse Cardiovascular Events;Myocardial energy expenditure;six minutes walk test;Traditional Chinese Medicine syndrome integral;NOD-like receptor thermal protein domain associated protein 3; | — |
Countries
CHINA
Contacts
Public ContactPeifen Chang
Dongzhimen Hospital of Beijing University of Chinese Medicine
Outcome results
None listed