Anterior cruciate ligament injury after reconstruction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ACLD participants: 1) Aged 18 - 40 years old; 2) Pre - operatively diagnosed with unilateral ACLD injury without collateral ligament meniscus or other structural injuries; 3) Injury duration over 1 month no moderate knee swelling walking pain; 4) Having one of these muscle strength imbalances: quadriceps or hamstring peak strength on the affected side below 85% of the contralateral side hamstring/quadriceps strength ratio below 70% or severe muscle atrophy (like in the vastus medialis) found on physical examination or ligament laxity difference between reconstructed and healthy sides less than 3mm but with knee instability or symptoms in the past 3 months or post - operative knee pain not due to inflammation; 5) Willing to participate and sign the consent form; ACLR participants: 1) Aged 18 - 40 years old; 2) Pre - operatively diagnosed with unilateral ACLD injury without collateral ligament meniscus or other structural injuries; 3) Single - bundle anatomic ACLR over 12 months post - surgery; 4) Having one of these muscle strength imbalances: quadriceps or hamstring peak strength on the reconstructed side below 85% of the contralateral side hamstring/quadriceps strength ratio below 70% or severe muscle atrophy (like in the vastus medialis) found on physical examination or ligament laxity difference between reconstructed and healthy sides less than 3mm but with knee instability or symptoms in the past 3 months or post - operative knee pain not due to inflammation; 5) Willing to participate and sign the consent form; 6) Good compliance agree to cooperate with treatment and exercise and can persist in completing the entire treatment process. Healthy participants: 1) Aged 18 - 40 years old; 2) In good health without neuromusculoskeletal diseases or other systemic diseases like respiratory or circulatory system diseases; 3) No major lower limb trauma or surgical history; 4) Willing to participate and sign the consent form; 5) Good compliance agree to cooperate with treatment and exercise and can persist in completing the entire treatment process.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for ACL Injury Subjects: 1. Presence of neuromusculoskeletal disorders or other systemic diseases such as polio; 2. Clinical diagnosis of knee osteoarthritis or radiological diagnosis of severe degenerative changes in the knee joint (Kellgren-Lawrence grade greater than I); 3. BMI > 30 kg/m²; 4. Inability to cooperate with the trial; 5. Missing clinical data. Exclusion Criteria for ACL Reconstruction Subjects: 1. Presence of neuromusculoskeletal disorders or other systemic diseases such as polio; 2. Clinical diagnosis of knee osteoarthritis or radiological diagnosis of severe degenerative changes in the knee joint (Kellgren-Lawrence grade greater than I); 3. Inability to cooperate with the trial; 4. BMI > 30 kg/m²; 5. Missing clinical data. Exclusion Criteria for Healthy Subjects: 1. Abnormal findings in physical examination or muscle strength testing (e.g. positive Lachman test positive McMurray test muscle atrophy etc.); 2. BMI > 30 kg/m²; 3. Missing clinical data; 4. Inability to cooperate with the experimenter.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Six-degree-of-freedom motion stability parameters of knee joint; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cross-sectional area of muscles around the knee;Electromyographic characteristic parameters during knee joint muscle movement;Elastic modulus of muscles around knee joint;radiographic parameters;Knee flexion / extension torque;Hamstring / quadriceps torque ratio;clinical scale;Characteristics of plantar pressure stability; | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Chinese Medicine