Influenza
Conditions
Interventions
intervention group:Kanggan mixture
Sponsors
Jiangsu Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria for influenza and the traditional Chinese medicine diagnostic criteria for Wind-Heat invading the Lung-Wei; 2. Aged between 18 and 65 years regardless of gender; 3. Within 48 hours of onset of illness; 4. Capable of completing ?all study-related assessments?; 5. Informed consent voluntary participation.The informed consent process should adhere to GCP guidelines.
Exclusion criteria
Exclusion criteria: 1. Participants who have received antiviral treatment for influenza infection for more than 48 hours before screening; 2. Participants with known severe renal impairment or those undergoing continuous renal replacement therapy hemodialysis or peritoneal dialysis; 3. Participants with mental changes or convulsions (such as slow response somnolence and restlessness); 4. Participants with severe gastrointestinal symptoms (such as severe nausea vomiting diarrhea and even dehydration); 5. Participants with any of the following critical illnesses: respiratory failure acute necrotizing encephalopathy infectious shock multiple organ dysfunction or other serious clinical conditions requiring intensive care; 6. Participants with tuberculosis measles HIV/AIDS or other infectious diseases; 7. Pregnant women (including those with a positive pregnancy test at enrollment) breastfeeding women or women within 2 weeks postpartum; 8. Participants determined by the investigator to have a history of allergy or severe intolerance to oseltamivir and herbal medicines; 9. Participants who are currently involved in or have participated in another influenza treatment trial within the past 28 days; 10. Patients deemed by the investigator as unlikely to comply with study visits self-assessment and interventions. 11.The blood test shows a significant increase in neutrophils, suggesting bacterial infectious bronchitis in the patient.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to disease remission; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Influenza Symptom Score;Time to antipyretic effect onset;Changes in Viral Load in Nasopharyngeal Secretions;Changes in Traditional Chinese Medicine (TCM) Syndrome Score from Baseline;Single-item influenza symptom score; | — |
Countries
China
Contacts
Public ContactHe Hailang
Affiliated Hospital of Nanjing University of Chinese Medicine
Outcome results
None listed