Co-morbid insomnia and obstructive sleep apnea
Conditions
Interventions
Control group:Placebo combined with Ciying minimally invasive acupuncture treatment
Experimental group:Luohua Anshen oral liquid combined with Ciying minimally invasive acupuncture treatment
Sponsors
Shanghai Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meet the above diagnostic criteria for obstructive sleep apnea syndrome and insomnia; (2) Age 18-80 years old; (3) Did not receive standardized OSA treatment; (4) No sleeping pills have been taken and no sleeping or psychotropic drugs have been taken in the past 2 weeks; (5) Those who can independently cooperate with each scale assessment; (6) Volunteer for participating in this study and sign informed consent and agree to accept follow-up observers.
Exclusion criteria
Exclusion criteria: (1) Patients with severe upper airway anatomical abnormalities including nasal septum deviation turbinate hypertrophy nasal polyps and nasal tumors tonsil hypertrophy above degree ? pharyngeal stenosis pharyngeal tumor pharyngeal mucosa hypertrophy tongue hypertrophy posterior root of tongue fall mandibular retraction and micrognathia; (2) Patients with a history of respiratory surgery and diabetes; (3) Patients who have been taking psychotropic drugs that affect the function of the central nervous system for a long time before screening such as antidepressants anti-schizophrenia drugs sedative hypnotics etc. and have not maintained a stable dose of medication for at least 4 weeks before screening in this experiment; (4) Patients with serious diseases of cardiovascular lung liver kidney or hematopoietic system endocrine system mental disorders brain organic diseases drug abuse or visual and hearing impairment; (5) Pregnant or lactating women; (6) alcoholics or drug addicts; (7) Those who have mental and consciousness disorders and are unable to communicate; (8) Patients who are allergic to the experimental drug or the ingredients contained in this protocol; (9) Participants who are participating in clinical trials of other drugs or who have participated in clinical trials of any drug (excluding vitamins and minerals) in the month prior to screening; (10) Unable to complete for other reasons considered by the experimenter or researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minimum oxygen saturation at night;Scores of Pittsburgh Sleep Quality Index Scale ;Apnea - hypopnea index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Scores of Insomnia Severity Index Scale;Scores of Epworth Sleepiness Scale;Scores of TCM symptom scale ; | — |
Countries
China
Contacts
Public ContactSun Yanjun
Shanghai Hospital of Traditional Chinese Medicine
Outcome results
None listed