immune thrombocytopenia
Conditions
Interventions
control group:Placebo + conventional treatment
treatment group:Guishao Shengxue decoction + conventional treatment
Sponsors
The Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1) Diagnosed with persistent or chronic ITP through hematological examination. 2) Children aged 1 to 14 years. 3) Patients with chronic or persistent ITP. 4) Obtained informed consent from each enrolled patient or their legally authorized guardian.
Exclusion criteria
Exclusion criteria: 1) Secondary thrombocytopenia caused by other conditions. 2) Patients with other hematological disorders rheumatic diseases malignancies or severe infectious diseases. 3) Patients who had recently received other traditional Chinese medicine treatments or participated in other clinical trials. 4) Patients with severe cardiac hepatic or renal dysfunction. 5) Patients with known allergies or a history of hypersensitivity to any component of Guishao Shengxue Decoction. 6) Patients were unable to comply with study protocols or follow-up requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical efficacy;mean platelet volume;plateletcrit;platelet distribution width;platelet count; | — |
Secondary
| Measure | Time frame |
|---|---|
| PAIgA;CD4/CD8 ratio;PAIgM;adverse events;hemoglobin;Baseline characteristics (sex, age, BMI, course of disease, platelet count);red blood cells;white blood cells;PAIgG;neutrophils;IL-6;CD8;CD3;CD4; | — |
Countries
China
Contacts
Public Contactwangwei
The Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Outcome results
None listed