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A randomized controlled clinical study on the efficacy and gait influence of modified Tungluo Zhibi Decoction combined with jingjin manipulation in the treatment of knee osteoarthritis under the theory of "equal emphasis on sinews bones and muscles"

A randomized controlled clinical study on the efficacy and gait influence of modified Tungluo Zhibi Decoction combined with jingjin manipulation in the treatment of knee osteoarthritis under the theory of "equal emphasis on sinews bones and muscles"

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000725
Enrollment
Unknown
Registered
2025-04-13
Start date
2025-02-26
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Control group:Celecoxib, glucosamine oral combined with physiotherapy
Treatment group:Tongluo Zhibi decoction combined with Jingjin manipulation

Sponsors

Xinwu District Hospital of Traditional Chinese Medicine Wuxi City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) It meets the diagnostic criteria and syndrome differentiation criteria of KOA; Age 40-75 years old gender is not limited; 3) unilateral knee pain; 4) no other relevant treatment has been taken in the past 1 month; 5) The patient voluntarily participated in the experiment and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1) Women who are breastfeeding pregnant or planning to become pregnant; 2) Those with a history of multiple drug allergies; 3) Those with severe primary diseases of the liver kidneys hematopoietic system endocrine system cardiovascular and cerebrovascular system and nervous system; 4) Patients with tuberculosis vertebral deformities or malignant tumors; 5) Those suspected of having a history of abuse of sedative-hypnotic drugs opioid analgesics or alcohol; 6) Those with skin diseases or infectious diseases; 7) Those with a history of gastric ulcers or gastric bleeding; 8) Those with mental disorders language disorders or motor function disorders who cannot cooperate; 9) Other patients who are not suitable or cannot apply this treatment method for other reasons.

Design outcomes

Primary

MeasureTime frame
myotonometry;Gait analysis detection;TUG test;

Secondary

MeasureTime frame
WOMAC score;

Countries

China

Contacts

Public Contactqiufeng

Xinwu District Hospital of Traditional Chinese Medicine Wuxi City

qiufeng4815@163.com18206189834

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026