Head and neck malignancies
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients with malignant tumors of nasal cavity sinus skull base and nasopharynx confirmed by pathological biopsy aged 18-70 years old regardless of gender; 2) There was no recurrence metastasis and abnormal intracranial diseases; 3) General cognitive function is normal the ability of daily living is basically normal no auditory visual language and other functional disorders; 4) Meet the above diagnostic criteria and give informed consent to this study.
Exclusion criteria
Exclusion criteria: 1) Patients who were diagnosed with allergic rhinitis and sinusitis before radiotherapy and did not improve significantly after long-term treatment; (2) Obvious abnormal liver and kidney function or allergic to the ingredients of Ziyin Qingheat Tongqiao recipe; 3) the expected survival time is less than 3 months; 4) unable to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Olfactory and taste function;Saccharin test;Clinical symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lund-Mackay score of nasal CT;Lund-Kennedy score of nasal endoscopy;Visual analogue scale of rhinosinusitis;QOD-NS Olfactory related questionnaire; | — |
Countries
China
Contacts
Department of Otolaryngology-Head and Neck Surgery China-Japan Friendship Hospital Beijing