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Clinical Study of Ziyinqingretongqiao Prescription for Prevention and Treatment of Radiation Therapy Injury

Clinical Study of Ziyinqingretongqiao Prescription for Prevention and Treatment of Radiation Therapy Injury

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000724
Enrollment
Unknown
Registered
2025-04-13
Start date
2025-04-15
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck malignancies

Interventions

Control group:Symptomatic treatment
Observation group:Based on symptomatic treatment, Herbal prescription for nasal irrigation(80ml) and inhalation(10ml in 20min)for 14 days

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Patients with malignant tumors of nasal cavity sinus skull base and nasopharynx confirmed by pathological biopsy aged 18-70 years old regardless of gender; 2) There was no recurrence metastasis and abnormal intracranial diseases; 3) General cognitive function is normal the ability of daily living is basically normal no auditory visual language and other functional disorders; 4) Meet the above diagnostic criteria and give informed consent to this study.

Exclusion criteria

Exclusion criteria: 1) Patients who were diagnosed with allergic rhinitis and sinusitis before radiotherapy and did not improve significantly after long-term treatment; (2) Obvious abnormal liver and kidney function or allergic to the ingredients of Ziyin Qingheat Tongqiao recipe; 3) the expected survival time is less than 3 months; 4) unable to cooperate.

Design outcomes

Primary

MeasureTime frame
Olfactory and taste function;Saccharin test;Clinical symptom score;

Secondary

MeasureTime frame
Lund-Mackay score of nasal CT;Lund-Kennedy score of nasal endoscopy;Visual analogue scale of rhinosinusitis;QOD-NS Olfactory related questionnaire;

Countries

China

Contacts

Public ContactLiu Jianfeng

Department of Otolaryngology-Head and Neck Surgery China-Japan Friendship Hospital Beijing

mmconfucius@163.com13621373926

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026