Endometritis complicated with infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for chronic endometritis in the 9th edition of "Obstetrics and Gynecology", and having evidence of positive hysteroscopy and histopathological examination results (including HE staining and CD138 immunohistochemistry); (2) Receiving assisted reproductive technology for infertility treatment in our hospital; (3) Meeting the traditional Chinese medicine syndrome differentiation criteria of damp-heat and blood stasis; (4) Aged between 20 and 42 years old; (5) Being informed about the content of this study, voluntarily participating, and signing the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of allergy to the drugs used in this study; (2) Patients complicated with diseases such as endometrial tuberculosis, endometriosis, endometrial cancer, acute genital tract infections, etc., as well as those with congenital malformations of the reproductive system; (3) Patients with malignant tumors, severe diseases of the hematopoietic system, circulatory system, and immune system, sexually transmitted diseases, severe liver and kidney insufficiency, and those with infections in other parts; (4) Patients with a history of treatment with antibiotics and immunosuppressants within the past 1 month; (5) Subjects who are currently receiving treatment with other traditional Chinese medicines or participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recovery status of the lesions under hysteroscopy;Histopathological changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in peripheral blood inflammatory factors;Safety examination;Evaluation of Traditional Chinese Medicine Syndrome Scores;Pregnancy outcome; | — |
Countries
China
Contacts
Affiliated Hospital of Jining Medical University