Irritable bowel syndrome with diarrhea
Conditions
Interventions
Pinaverium bromide group:Pinaverium bromide
Sponsors
Hubei Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) meet the Rome IV diagnostic criteria for diarrhea-predominant irritable bowel syndrome; (2) Age: 18-70 years old; (3) IBS-SSS with moderate to severe symptoms score =175; (4) the course of disease was at least 6 months; (5) no mental disorders with normal communication skills; (6) those who signed informed consent and voluntarily accepted the intervention method of this project. Note: Patients who met the above 6 criteria were included in this study.
Exclusion criteria
Exclusion criteria: (1) organic intestinal diseases or systemic diseases affecting digestive tract function (such as gallbladder pancreatitis hyperthyroidism diabetes etc.); (2) previous intestinal surgery; (3) taking medications that may affect bowel function (such as montmorillonite powder Dicetel cisapride or other herbal medicine) or taking any medication for IBS within 2 weeks before enrollment; (4) patients who received moxibustion treatment within 30 days before enrollment; (5) patients with serious primary diseases such as cardiovascular system liver kidney mental disorders and cognitive impairment; (6) pregnant or lactating women; (7) patients with local skin damage or temperature sensory disturbance patients with severe Yin deficiency and fire hyperactivity syndrome patients with solid heat syndrome and patients with allergy to ginger juice and moxibustion. (8) Participants in other projects. Note: Patients who met any of the above criteria were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IBS-SSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| GAD-7;BDI-II;IBS-QOL;Inflammatory response markers;EQ-5D; | — |
Countries
China
Contacts
Public ContactZhongyu Zhou
Hubei Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed