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A randomized controlled clinical study of Professor Lijing's empirical prescription for transdermal topical treatment of chronic heart failure

A randomized controlled clinical study of Professor Lijing's empirical prescription for transdermal topical treatment of chronic heart failure

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000687
Enrollment
Unknown
Registered
2025-04-10
Start date
2025-01-14
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure

Interventions

experimental group:Transdermal topical use: Professor Zhang Lijing's experience prescription (Astragalus, Mai Dong and other confidential prescriptions) tincture transdermal external use
control group:Transdermal topical application of Professor Zhang Lijing's experience prescription tincture placebo

Sponsors

Dongzhimen Hospital Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Age= 18 years old and = 85 years old, gender is not limited; (2) meet the diagnostic criteria; (3) TCM dialectics is a patient with heart failure that conforms to the pattern of qi deficiency and blood stasis; (4) Voluntarily participate, understand and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Those who are in the acute stage of heart disease and whose condition is not controlled; (2) Patients with valvular heart disease, cardiomyopathy, coronary myobridge, aortic dissection, acute pericarditis, acute pericarditis, and cardiac insufficiency; (3) Patients with congenital heart disease; (4) Patients with uncontrolled grade 3 hypertension (systolic blood pressure = 180mmHg and/or diastolic blood pressure =110mmHg), severe cardiopulmonary insufficiency, severe arrhythmia, serious primary diseases such as liver, kidney and hematopoietic system, or serious diseases (such as tumors, etc.) and mental illness that affect their survival; (5) Patients with abnormal liver and kidney function indicators (ALT, AST, and Scr exceed the upper limit of the normal reference range by 1.5 times); (6) Patients with allergies, or allergies to multiple drugs and foods, or patients who are known to be allergic to the test drugs (including their components); (7) Those who have a pregnancy plan or pregnant or lactating women; (8) Patients with malignant tumors; (9) Patients with cerebrovascular or hematologic primary diseases; (10) Patients who have participated in other clinical trials in the past 1 month.

Design outcomes

Primary

MeasureTime frame
LVEF;liver function tests;hs-CRP;ECG;Myocardial injury markers;blood coagulation tests;NLR;Seattle Angina Scale;NT-proBNP;IL-6;Urinalysis;TCM Symptom Points;

Countries

China

Contacts

Public ContactZHANG Lijing

Dongzhimen Hospital Beijing University of Chinese Medicine

dzmyyccu@163.com010-84013181

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026