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The clinical efficacy study of acupuncture based on the brain-gut axis in regulating the vagus nerve for patients with functional constipation and depression.

The clinical efficacy study of acupuncture based on the brain-gut axis in regulating the vagus nerve for patients with functional constipation and depression.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000680
Enrollment
Unknown
Registered
2025-04-08
Start date
2025-05-07
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

constipation and depression

Interventions

Group A:Electroacupuncture stimulation at bilateral Zusanli (ST36) Shousanli (LI10) Tian Shu (ST25) and Neiguan (PC6) points.

Sponsors

The First Peoples Hospital of Zhangjiagang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Those who meet the diagnostic criteria for functional constipation with depression. (2) Patients aged between 20 and 60 years. (3) Individuals who agree to undergo and complete the treatment cooperate with this study accept telephone or outpatient follow-up and sign the informed consent form. (4) Currently not using medications for diseases related to this study or the time since the last treatment for constipation or depression is more than 1 month prior to the treatment in this study.

Exclusion criteria

Exclusion criteria: (1) Those with a history of abdominal or rectal-anal surgery. (2) Irritable bowel syndrome and constipation caused by organic or pharmacological factors; constipation secondary to endocrine metabolic or neurological disorders. (3) Those with concomitant heart liver or kidney damage cognitive dysfunction aphasia or those unable to cooperate with sample collection and treatment. (4) Pregnant or breastfeeding women or those with pregnancy plans within the past three months. (5) Those with coagulation disorders or those who have been using anticoagulants such as warfarin or heparin.

Design outcomes

Primary

MeasureTime frame
Self-initiated bowel movements;

Secondary

MeasureTime frame
Adrenocorticotropic hormone;Stool characteristics;Depressive condition;Cortisol;Heart rate variability;

Countries

China

Contacts

Public ContactGE Lingling

The First Peoples Hospital of Zhangjiagang City

834140112@qq.com18862637831

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026