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The effect of different timing of acupuncture intervention on the pregnancy outcomes of FET: a prospective cohort study

Clinical Observation on the Effect of Acupuncture Therapy at Different Time Points on the Pregnancy Outcomes in FET

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000678
Enrollment
Unknown
Registered
2025-04-07
Start date
2025-04-25
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Group B (acupuncture during FET cycle):Acupuncture treatment during transplantation cycle only
Group C (no acupuncture):No acupuncture treatment
Group A (acupuncture before FET cycle):Acupuncture treatment within three months prior to embryo transfer

Sponsors

Sichuan Jinxin Xinan Womens and Childrens Hospital Chengdu City Sichuan Province
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
21 Years to 37 Years

Inclusion criteria

Inclusion criteria: Patients who fulfill all of the following criteria will be included. (1) Infertile patients are planning to undergo FET; (2) Aged 21-38 years; (3) Having frozen embryos (at least 1 good quality blastocyst or 2 high-quality cleavage embryos); (4) Adopted hormone replacement therapy (HRT) as the endometrial preparation regimen; (5) Hysteroscopy was completed with no abnormality; (6) Signed informed consent voluntarily.

Exclusion criteria

Exclusion criteria: Patients who fulfill any of the following criteria will be excluded. (1) Those who intend to perform preimplantation genetic testing (PGT) of embryos; (2) History of uterine malformation (e.g. unicornuate uterus bicornuate uterus untreated septate uterus) and other untreated diseases that can damage the endometrial cavity (e.g. uterine adenomyosis submucous myoma uterine adhesion or scarred uterus). (3) History of endocrine metabolic diseases such as uncorrected hyperprolactinemia hyperandrogenism thyroid dysfunction and chronic adrenal cortical dysfunction. (4) History of recurrent miscarriage; (5) Acupuncture syncope and other conditions that are prohibited to use acupuncture for example high risk of hemorrhage serious infection or skin diseases(e.g. allergies ulcers or scars) at the acupuncture site; (6) Acupuncture treatment in the past 3 months.

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy;

Secondary

MeasureTime frame
Health economics indicator;Endometrial receptivity;Other pregnancy-related indicators: biochemical pregnancy, ongoing pregnancy, ectopic pregnancy, live birth, first-trimester pregnancy loss. ;Cycle cancellation;

Countries

China

Contacts

Public ContactJie Yang

Chengdu University of Traditional Chinese Medicine; Sichuan Jinxin Xinan Womens and Childrens Hospital Chengdu City Sichuan Province

jenny_yang_jie@126.com+86 138 8229 6714

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026