Immunoglobulin A nephropathy
Conditions
Interventions
test group:Buzhongqingli decoction (Basic composition: Codonopsis radix 10g Radix astragali 10g Radix scutellaria 15g Bixie 15g Coicis seed 15g
Add flavor: pharyngeal congestion with dandelion 10g forsythe 10g
If loose stool was found more than twice a day 15g white lentil and 15g yam were added. For turbid urine add plantain 15g Shiwei 15g) 1 dose a day each dose decoction 200ml take twice morning and even
Sponsors
Xiyuan Hospital of CACMS
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Renal biopsy confirmed IgA nephropathy; (2) TCM syndrome differentiation conforms to the syndrome of spleen deficiency and damp-heat; (3) age between 18 and 65 years old; (4) CKD stage 1-3 estimated glomerular filtration rate (eGFR)=30ml/min/1.73m2 (calculated by EPI formula); (5) 24-hour urinary protein =2.0g; (6) voluntarily accept this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) secondary IgA nephropathy; (2) complicated with serious diseases affecting the survival of patients including serious cardiovascular diseases cerebrovascular diseases malignant tumors hematopoietic system diseases; (3) IgA nephropathy with malignant hypertension and rapid progression and deterioration of renal function; (4) breastfeeding pregnancy or planned pregnancy during the study period; (5) those with mental disorders who cannot receive normal treatment; (6) participating in other clinical investigators; (7) patients with allergy to study drugs or allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UA;TCMSS;CREA;24-hour urinary protein quantification;ACR;urine RBC/HPF;BUN;GFR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Triglycerides;Total Cholesterol;Blood Glucose; | — |
Countries
China
Contacts
Public ContactYu Dajun
Xiyuan Hospital of CACMS
Outcome results
None listed