diminished ovarian reserve
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Female patients between the ages of 18-40 years; (2) Meets the diagnostic criteria of DOR; (3) Those who meet the syndrome of qi and blood deficiency in traditional Chinese medicine; (4) Those who voluntarily participate in this clinical observation and can cooperate with the requirements of treatment and follow-up; (5) The informed consent process complies with the regulations and the informed consent form is signed.
Exclusion criteria
Exclusion criteria: (1) Pregnant women lactating women or women who have planned to conceive in the past six months; (2) Patients with other endocrine diseases (such as endometriosis polycystic ovary syndrome thyroid disease hyperprolactinemia adrenal tumors etc.) and organic lesions of reproductive organs in addition to DOR; (3) Drugs or complementary treatments related to DOR (including: acupuncture traditional Chinese medicine Chinese patent medicine and other complementary alternative medicine therapies) in the past 8 weeks; (4) Those who have used hormone drugs or drugs that affect reproductive endocrine and metabolism in the past 12 weeks; (5) Patients with organic lesions in important organs such as heart lungs liver kidneys etc. or patients with mental disorders and other reasons that cannot cooperate with the test; (6) Those who are allergic to the test drug and its excipients; (7) Those who are undergoing other aspects of treatment or participating in other clinical experimental research; (8) Those who are judged by the investigator to be inappropriate to be selected for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Follicle-Stimulating Hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| estradiol;luteinizing hormone;anti-Mullerian hormone;Treg;IL-2;growth differentiation factor 9;T helper cell 17;BMP10;IL-4;Traditional Chinese Medicine Syndrome Scoring;GATA-3;transforminggrowthfactor-ß;interferon-?;IL-10;T-bet;antral follicle counting;BMP-15; | — |
Countries
China
Contacts
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine