Colorectal cancer
Conditions
Interventions
Control group:Quxie capsule placebo
Sponsors
Xiyuan Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Age 60-85 years old both sexes; 2) Colorectal cancer diagnosed by pathology; 3) Clinical stage IV with measurable lesions; 4)ECOG 0-2; 5) predicted survival time =6 months; 6) voluntarily participate in the study and sign the informed consent; 7) Good compliance was predicted and the efficacy and adverse reactions could be followed up according to the protocol.
Exclusion criteria
Exclusion criteria: 1) patients with radical surgery or potential transformation; 2) Diarrhea > 3 times/day or grade II or above diarrhea (CTCAE v4.03); 3) Gastrointestinal bleeding fecal occult blood positive PLT < 80×109/L; 4) Severe cardiovascular system complications cerebrovascular system complications active hepatitis severe liver and kidney dysfunction; 5) There are many factors affecting the absorption of oral drugs such as inability to swallow and intestinal obstruction; 6) any unstable condition or condition that may compromise the patient's safety and adherence to the study such as severe mental illness such as schizophrenia; 7) patients who will be enrolled in or are currently enrolled in other clinical trials. (8) patients allergic to the drug. 9) Patients with unresected primary intestinal lesions and large tumor burden.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM related main symptoms;Progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Edmund Cancer Quality of Life Scale;Tumor markers;Median survival time;TCM spleen deficiency scale;TCM symptom score;Quality of Life instrument for colorectal cancer patients; | — |
Countries
CHINA
Contacts
Public Contactyangyufei
Xiyuan Hospital China Academy of Chinese Medical Sciences
Outcome results
None listed