Ulcerative colitis
Conditions
Interventions
Combination group:Jianggui Wenzhong Decoction + Mesalazine
Western medicine group:Mesalazine
Sponsors
Hubei Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) It meets the diagnostic criteria for remission of ulcerative colitis in Western medicine (modified Mayo total score =2 points and no single sub-score > 1 point); (2) Meet the criteria for clinical response and histological response; (3) Those who meet the TCM syndrome differentiation as spleen-kidney Yang deficiency; (4) Age 18-70 years old gender is not limited; (5) Voluntarily participate in and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Active persistent fulminant UC patients who are taking second-line therapy or additional therapy hormone dependent or hormone ineffective; (2) Severe complications such as local stenosis intestinal obstruction intestinal perforation massive bleeding rectal polyps toxic colon dilatation colon cancer rectal cancer and anal disease; (3) Patients with Crohn's disease undefined colitis ischemic colitis radiation colitis diverticulosis with colitis under the microscope and diarrhea and other infectious diarrhea; (4) Patients with liver kidney hematopoietic system endocrine system and other serious primary diseases and mental disorders; (5) Women who are pregnant or preparing to become pregnant breastfeeding women; (6) Allergic to the investigational drug and its ingredients; (7) Those who had used sulfoazopyridine (SASP) and 5-amino-salicylic acid (5-ASA) to no avail.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory related examination;TCM syndrome score;Medication compliance;Life quality;Endoscopic mucosal histological score; | — |
Countries
China
Contacts
Public ContactLIN AIZHEN
Hubei Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed