coronary heart disease with depression
Conditions
Interventions
HJSSJW group:Take Western medicine in conjunction with HJSSJW granules.
control group:Take Western medicine in conjunction with HJSSJW granule placebo.
Sponsors
Hangzhou TCM Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with coronary heart disease who have undergone percutaneous coronary stent implantation less than 3 months ago and are receiving routine Western medical treatment. 2. Patients with the traditional Chinese medicine syndrome of "stasis toxin and depression interconnection." 3. Patients with a heart function classification of = NYHA Class II and an ejection fraction of = 45%. 4. Middle-aged and elderly population (aged 45-80 years).
Exclusion criteria
Exclusion criteria: 1. cTnI > 0.4 µg/L. 2. Patients taking psychiatric medications. 3. History of stroke (cerebral hemorrhage subarachnoid hemorrhage cerebral thrombosis cerebral embolism or stroke of unspecified type) within the past 6 months. 4. Uncontrolled hypertension (= 180/100 mmHg) or hypotension (< 90/60 mmHg). 5. Patients with malignant arrhythmias (ventricular tachycardia rapid atrial fibrillation atrial flutter second-degree type II or higher atrioventricular block complete bundle branch block) that have recently recurred. 6. Patients with severe hepatic and renal dysfunction (creatinine clearance rate = 40 ml/min serum transaminase = 2 × the upper limit of clinical reference value) other serious primary diseases that affect life expectancy cancer or severe psychiatric disorders. 7. Pregnant planning to become pregnant or breastfeeding women. 8. Known bleeding tendency or bleeding disorders uncontrollable coagulation mechanism disorders active bleeding within the past 2 weeks invasive diagnostic or therapeutic proced
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major Adverse Cardiovascular Events (MACE); | — |
Secondary
| Measure | Time frame |
|---|---|
| hipline;Hamilton Depression Scale (HAMD-24);glycosylated hemoglobin;waistline;Traditional Chinese Medicine Syndrome Scoring;Hamilton Anxiety Scale (HAMA-14);Coronary CTA/CAG;Pittsburgh Sleep Quality Index (PSQI);clinical outcome events;Holter Monitoring;Echocardiography;Lipid Profile;Seattle Angina Questionnaire (SAQ); | — |
Countries
China
Contacts
Public ContactZhu Aisong
Zhejiang Chinese medical university
Outcome results
None listed