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A Cross-over Randomized Controlled Study on the Dose-Effect Relationship of the Cerebral Effect of Acupuncture at Weizhong Point (BL40) in Patients with Lower Limb Motor Dysfunction after Cerebral Infarction

A Cross-over Randomized Controlled Study on the Dose-Effect Relationship of the Cerebral Effect of Acupuncture at Weizhong Point (BL40) in Patients with Lower Limb Motor Dysfunction after Cerebral Infarction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000598
Enrollment
Unknown
Registered
2025-03-26
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower limb motor impairment after stroke

Interventions

Control group:The following limbs twitch for 1 time, within 1min. Two weeks later, the intervention methods of the two groups were exchanged, and the operation was the same as above.
Experimental group:The following limbs twitch for 3 times, the time is 1min. Two weeks later, the intervention methods of the two groups were exchanged, and the operation was the same as above.

Sponsors

The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Meeting the diagnostic criteria for ischemic stroke; (2) Within 30 days after the first stroke with stable vital signs (Glasgow Coma Scale (GCS) score > 8 points); (3) Infarction focus in the basal ganglia area (internal capsule) and/or corona radiata (diameter > 1.5 cm) accompanied by lower limb motor dysfunction (muscle strength = grade 4-) and may be combined with upper limb motor dysfunction (National Institutes of Health Stroke Scale (NIHSS) score is 3-15 points); (4) Aged between 40 and 70 years old; (5) Right-handed; (6) Those who provide informed consent and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Dependence on daily activities before this stroke; (2) Infection at the acupuncture site and/or intolerance to acupuncture treatment; (3) Suffering from other serious concomitant diseases (aphasia moderate to severe edema of the lower limbs lower limb venous thrombosis lower limb arteriosclerosis obliterans diabetic lower limb vascular disease peripheral neuropathy spinal cord lesions brain trauma intracranial infection brain tumors etc.) and secondary diseases (such as heart liver and kidney failure etc.); (4) Having contraindications for MRI examination (claustrophobia surgical implantation of metal devices etc.); (5) Scores on the Mini-Mental State Examination (MMSE): less than 17 points for illiterate people less than 20 points for those with primary school education and less than 24 points for those with education above middle school level; scores on the Hamilton Rating Scale for Depression (HAMD-17) > 17 points; scores on the Hamilton Anxiety Rating Scale (HAMA) = 14 points.

Design outcomes

Primary

MeasureTime frame
FMA-L;fMRI;

Secondary

MeasureTime frame
Use muscle strength tester to measure lower limb strength of affected side;Questionnaire on the Sensation of Deqi;MMT-L;

Countries

China

Contacts

Public ContactXuesong Ren

The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine

hebrxs@126.com13920980943

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026