Erectile dysfunction
Conditions
Interventions
control group:Sildenafil Citrate Tablets
Test group:Huashi Tongbi prescription
Sponsors
Medical Ethics Committee of Xiyuan Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Male
Age
22 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) In line with the dialectical standards of traditional Chinese medicine for ED with hot and humid spleen (2) IIEF-5 score =21 points (3)22=age=50 years old (4) Those who have a fixed sexual partner and have a regular sex life have sex once a week or more and cooperate with those who have completed this experiment. (5) Right hand (6) Voluntarily sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Persons with severe traumatic ED (2) Those with severe cardiovascular and cerebrovascular diseases organic brain injury liver and kidney insufficiency sickle cell anemia multiple myeloma leukemia and other serious diseases (3) Those with severe intestinal diseases such as ulcerative colitis Crohn's disease etc. that may affect the fecal flora (4) People with mild moderate and severe anxiety and depression who need to take anti-anxiety and depression drugs regularly for a long time (5) People with allergies who are prone to allergies to drugs (6) Patients who have taken drugs that may affect this study within the past month or have participated in other clinical researchers (7) Those who have a birth plan during the treatment period and within 3 months after the end of the treatment (8) There are contraindications to magnetic resonance imaging.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| International Erectile Function Index Scale-5 Score;TCM syndrome grading quantitative score; | — |
Secondary
| Measure | Time frame |
|---|---|
| sex hormone;Blood lipids;Immunofunction-related markers;Inflammatory factors;Modified sexual quality of life questionnaire;Aging-related markers;Self-Rating Fatigue Scale;Erectile Quality Scale;Vascular medium;Serum metabolomics;Sex hormone-binding globulin;Fecal metabolomics;Gastrointestinal hormones;Male Self-Rating Sexual Desire Scale;blood glucose;Self-rating Depression Scale;Bilirubin;Brain structure and function MRI;Self-rating Anxiety Scale;Markers related to brain function;Pittsburgh sleep quality Index;insomnia Severity Index;Gut microbiota;oxidative stress markers; | — |
Countries
Chine
Contacts
Public ContactJiayou Zhao
none
Outcome results
None listed