amnestic mild cognitive impairment
Conditions
Interventions
Aromatherapy trial group:Sniffing was performed once for 30 minutes from 19 to 21 o 'clock every day for 12 weeks. Each time use an eyedropper to absorb the suhexiang essential oil put 3 drops in the
Control group:Sniffing was performed once for 30 minutes from 19 to 21 o 'clock every day for 12 weeks. Each time use an eyedropper to absorb pure water drop 3 drops in the center of a circular filter
Sponsors
Hebei Medical University
Eligibility
Sex/Gender
All
Age
68 Years to 85 Years
Inclusion criteria
Inclusion criteria: According to the diagnostic criteria for aMCI proposed by Petersen in 2004: 1. Age =65 years old; 2. A history of memory impairment of =3 months confirmed by informed persons; 3. Have basically normal daily living ability (ADL=22 points); 4. Clinical dementia rating (CDR) score 0.5 points; 5. Simple Mental State Examination Scale (MMSE) score < 27; 6. Normal olfactory function; Right-handed; 7. Subjects agree to join the experiment and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Alcohol or drug dependence within the past six months; 2. Combined with aphasia or severe visual impairment or hearing impairment; 3. Cognitive decline due to vascular factors or depression; 4. There are brain structural abnormalities that lead to cognitive impairment: such as congenital mental retardation brain trauma etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA;MMSE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hcy;Quantitative electroencephalogram;BDNF; | — |
Countries
China
Contacts
Public ContactChen Haiying
Hebei Medical University
Outcome results
None listed