Uremic skin itching
Conditions
Interventions
Treatment group:Bu Shen Qu Du Tang 50ml orally taken twice a day for 14 consecutive days.
control group:Cetirizine tablets 10mg pro qd
Sponsors
Fujian University of Traditional Chinese Medicine Affiliated Second People's Hospital
Eligibility
Sex/Gender
All
Age
16 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1) Referring to the prognosis and quality of life of kidney disease patients at the American Kidney Disease Foundation in the year patients with CKD stage 5 who have undergone hemodialysis replacement therapy (CKD stage 5D) were selected based on the glomerular filtration rate (GFR) level and chronic kidney disease (CKD) staging. 2) According to the diagnostic criteria for UP in "Chinese Clinical Dermatology": 1) Skin diseases with no primary skin damage but mainly itching itching occurring at least 3 days within 2 weeks and itching occurring several times a day for several minutes each time affecting the patient's quality of life; 2) Skin itching that appears in a specific pattern and lasts for more than 6 months Itching score is greater than 0. 3) Constipation diagnosis criteria: The Wexner Constipation Rating Scale with a total score of 15 or above indicates constipation. 2. Inclusion criteria 1) Referring to the "Standard Operating Procedures for Blood Purification" edited by Chen Xiangmei published by People's Health Press in November 2020 all patients meet the diagnostic criteria for end-stage chronic kidney failure and have undergone regular dialysis for = 3 months with a weekly dialysis time of = 8 hours and sufficient dialysis [single room Kt/V (spKt/V) = 1.2]; 2) Skin itching score>0 points; 3) Stable condition; 4) Age over 16 years old gender not limited race limited to yellow people only; 5) Voluntary participation in research.
Exclusion criteria
Exclusion criteria: 1) Patients who do not meet the inclusion criteria; 2) Patients with skin related diseases patients with diabetes systemic lupus erythematosus vasculitis and other systemic diseases that can cause skin itching; 3) Drug or toxin poisoning; 4) Patients who are unwilling to cooperate unable to cooperate and unable to collect data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation score;Itchy rating;serum phosphorus; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum creatinine;Serum urea nitrogen;C-reactive protein;Serum calcium;Comprehensive evaluation of quality of life; | — |
Countries
China
Contacts
Public ContactZhang PengSheng
Fujian University of Traditional Chinese Medicine Affiliated Second People's Hospital
Outcome results
None listed