Parkinson's disease
Conditions
Interventions
control group:sham acupuncture
treatment group:acupuncture
Sponsors
Beijing Hospital of Tradional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1)It meets the diagnostic criteria of the PD-MCI comprehensive assessment model in the Chinese guidelines for the diagnosis and treatment of mild cognitive impairment in Parkinson's disease (2020 edition); (2)Age 50 to 75; (3)Montreal cognitive assessment scale score =20 and =25; (4)Have received standardized medication for at least 3 months have fixed anti-PD drug treatment plan no drug adjustment plan in the next 3 months; (5)H-Y stage =2.5 grade -LRB-grade 1: symptoms of unilateral limb involvement; grade 1.5: symptoms of unilateral limb involvement with trunk involvemeGraderade 2: symptoms of bilateral limb involvement with no balance impairmeGraderade 2.5: mild bilateral limb involvement with mild balance impairmeGraderade 3: moderate bilateral limb involvement with significant postural instability with many functional limitations in the patient but ability to fend for himself and slow turning; grade 4: severe bilateral limb involvement with difficulty walking or standing independently; gradeBedriddendden or living in a wheelchair. Grades 1-2.5 are in patients with early PD grades 3-4 in patients with intermediate PD and grades 5 in patients with advanced PD; (6)I have not received acupuncture treatment for PD-MCI or PD in the last 3 months; (7)Sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1)Secondary Parkinson syndrome or Parkinson's plus syndrome; (2)People with Alzheimer's disease Parkinson's disease dementia cerebrovascular disease severe diabetes traumatic brain injury as well as drugs and alcohol can explain cognitive impairment and other serious mental illnesses; (3)Is currently taking or has taken a medication in the past 3 months that improves cognitive function examples include cholinesterase inhibitors (rivastigmine donepezil and galantamine) memantine or over-the-counter drugs that claim cognitive benefits; (4)Patients treated with neurosurgery (deep brain stimulation) psychotherapy or repetitive transcranial magnetic stimulation; (5)Patients with depression Beck Depression Inventory-II =20; (6)Patients participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Verbal fluency test;clock drawing test; | — |
Secondary
| Measure | Time frame |
|---|---|
| verbal fluency test;Montreal cognitive assessment;Rey auditory word learning test;Unified Parkinson's disease rating scalesection ?;clock drawing test;Proportion of patients with H-Y stage more advanced than at enrollment;TMT-A;Parkinson's Disease Questionnaire-39;Hooper visual organization test;Boston naming test; | — |
Countries
China
Contacts
Public ContactPeng Chen
Beijing Hospital of Tradional Chinese Medicine
Outcome results
None listed