chemotherapy induced peripheral neuropathy
Conditions
Interventions
Simple acupuncture group:acupuncture+ electroacupuncture treatment for 4 weeks three times a week
Observation and Follow up Group:N/A
Simple moxibustion group:moxibustion treatment for 4 weeks three times a week
Acupuncture and moxibustion group:acupuncture+ electroacupuncture +moxibustion treatment for 4 weeks three times a week
Sponsors
Sichuan Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Female patients aged = 18 years and = 75 years old; 2. Primary invasive breast cancer confirmed by histology; 3. Completed adjuvant chemotherapy based on paclitaxel drugs; 4. After chemotherapy report grade 1 or higher CIPN symptoms for more than 2 weeks as defined by the National Cancer Institute Common Toxicity Criteria (NCI-CTCAE) 5.0. 5. Voluntarily join this study sign an informed consent form have good compliance and are willing to cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1.Suffering from other malignant tumors; 2.Peripheral neuropathy before chemotherapy (such as alcoholism diabetes congenital neuropathy toxic neuropathy nerve compression or injury neuroma etc.); 3.Before enrollment they had received acupuncture and moxibustion or moxibustion treatment due to CIPN; 4.Pregnancy or breastfeeding; 5.During the period of receiving adjuvant chemotherapy; 6.Prophylactic or therapeutic use of neurological function improving drugs such as duloxetine and pregabalin during and/or after chemotherapy; 7. Suffering from serious accompanying diseases or other comorbidities that may interfere with the planned treatment or any other circumstances that the researcher deems unsuitable for the patient to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom assessment of chemotherapy induced peripheral neuropathy; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life; | — |
Countries
China
Contacts
Public ContactJunjie Li
Sichuan Cancer Hospital
Outcome results
None listed