Irritable Bowel Syndrome with Diarrhea (IBS-D)
Conditions
Interventions
Positive drug control group:Oral bifidobacterium triple live tablet, 4 tablets twice a day for 8 weeks.
Sponsors
Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) 18 years old to 65 years old; (2) Meet the diagnostic criteria for IBS-D according to Rome IV; (3) Symptoms have been present for at least 6 months and persist for at least 3 months; (4) Informed consent signed by the patient themselves or by their immediate family members. Patients who meet the above 1-4 criteria can be included in this study. Patients with warning signs should undergo targeted auxiliary tests to rule out organic diseases. Warning signs include age >40 years positive stool blood fecal occult blood test nocturnal bowel movements anemia abdominal mass ascites fever unexplained weight loss of 4-5 kg or more in the last year and a family history of colorectal cancer and IBD.
Exclusion criteria
Exclusion criteria: (1) Weight loss of more than 4-5 kg for unknown reasons in the past year blood in stool tumors repeated fever and other diseases history of other intestinal infections or non-infectious diseases such as inflammatory bowel disease ischemic bowel disease intestinal polyps functional diarrhea etc.; (2) Suffering from serious heart liver kidney hematopoietic system diseases systemic malnutrition or undergoing anal or rectal surgery; (3) Patients who have received acupuncture in the past 30 days or who have taken medication in the past 2 weeks; (4) Patients with severe cardiovascular disease liver or renal insufficiency poor coagulation function etc.; (5) Patients with mental disorders; (6) Women who are menstruating pregnant or breastfeeding; (7) Participants who have participated in or are participating in other clinical trials within the last 3 months that may interfere with this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| )IBS-SSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| IBS-GIS;The bowel movement is not completely felt;Safety result;pain degree;defecation times;flatulence;Stool urgency;Fecal character assessment; | — |
Countries
China
Contacts
Public ContactZheng Hui
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed