Knee Osteoarthritis with Synovitis.
Conditions
Interventions
Placebo Group:Apply two pieces of placebo plasters externally to the medial and lateral edges of the patella, for 8 hours each time, once daily, continuously for 2 weeks.
Huaiyang Zhitong Plaster Group:Apply two pieces of Huaiyang Zhitong Plaster externally to the medial and lateral edges of the patella for 8 hours each time once daily continuously for 2 weeks.
Sponsors
The Affiliated Traditional Chinese Medicine Hospital Southwest Medical Universit.
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Meets the diagnostic criteria for knee osteoarthritis knee synovitis and Traditional Chinese 2) Medicine syndromes of cold and damp obstruction. 3) Kellgren & Lawrence grading for knee osteoarthritis is = Grade II. 4) No treatment for knee osteoarthritis has been administered in the past month. 5) Age between 30 and 70 years regardless of gender.
Exclusion criteria
Exclusion criteria: 1) Patients with secondary knee osteoarthritis caused by other conditions such as those resulting from joint trauma congenital or hereditary diseases etc. 2) Patients with allergies to the study drug or those with skin ulcerations rashes infections or other issues in the knee joint area. 3)Pregnant or breastfeeding women or those planning to conceive use sperm donation or egg donation within the month. 4) Patients who have participated in any other clinical trials in the past three months. 5) Patients unwilling to accept study measures or unable to cooperate due to mental illness or other conditions. 6) Patients with severe primary diseases of the heart brain liver kidneys or hematopoietic system. 7) Patients who have received medication for knee osteoarthritis or knee synovitis within the past week which may affect the evaluation of efficacy and safety endpoints. 8) Any other factors deemed by the investigator to render the patient unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC Score;Visual Analog Scale (VAS) Score;Clinical effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of fluid accumulation in knee joint under color ultrasound;Security assessment; | — |
Countries
China
Contacts
Public ContactHouyin Shi
The Affiliated Traditional Chinese Medicine Hospital Southwest Medical Universit.
Outcome results
None listed