Diarrheal irritable bowel syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients with diarrheal IBS who meet the diagnostic criteria; (2) TCM syndrome differentiation belongs to liver depression and spleen deficiency syndrome; (3) Age between 18 and 65 years old gender is not limited; (4) Inspection indicators: the general situation is good; Blood urine stool routine (-) bacterial culture (-) fecal occult blood (-); Liver and kidney function and blood sugar were normal abdominal B was abnormal. Thyroid function was normal. Colonoscopy showed no morphological or histological abnormalities. (5) Sign the patient's informed consent voluntarily.
Exclusion criteria
Exclusion criteria: (1) Patients with organic intestinal lesions; (2) Patients with other types of IBS; (3) Simultaneous use of drugs that affect the efficacy evaluation of this study (such as Smecta desutes Cisapride or traditional Chinese medicine etc.) Of patients; (4) Suffering from other organic diseases of the digestive system tumors confirmed by colonoscopy or barium enema inflammatory bowel disease intestinal tuberculosis or other organic diseases or suffering from systemic diseases causing diarrhea such as lactase deficiency hyperthyroidism etc.; (5) with fever anemia blood in the stool or serious heart liver kidney endocrine and metabolic disorders hematopoietic system disorders malignant tumors or mental disorders and other diseases in the acute stage; (6) Pregnant or lactating women; (7) There are scars or sensory disorders in the body surface area of the acupuncture points involved in this study resulting in the inability to perform acupuncture.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bristol symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cholesterol 7 a-hydroxylase;Self-Rating Depression Scale (SDS);Irritable Bowel Syndrome Severity Scale (IBS-SSS);Irritable Bowel Syndrome Gastrointestinal Symptom Scale (GSRS-IBS);7 alpha-hydroxy-4-cholesterene-3-one;Self-Rating Anxiety Scale (SAS);Numerical Evaluation Scale for Abdominal Pain (NRS);Total bile acids;Deoxycholic acid;Cholic acid; Effective Response Rate (ERR);IBS Quality of Life Scale (IBS-QOL);TCM syndrome score scale;Intestinal flora;Lithocholic acid; | — |
Countries
People's Republic of China
Contacts
Shanghai Seventh People's Hospital