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Clinical study on the treatment of diarrheal irritable bowel syndrome with liver-stagnation and spleen-deficiency syndrome by acupuncture and moxibustion

Clinical study on the treatment of diarrheal irritable bowel syndrome with liver-stagnation and spleen-deficiency syndrome by acupuncture and moxibustion

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000547
Enrollment
Unknown
Registered
2025-03-18
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrheal irritable bowel syndrome

Interventions

Sham acupuncture group:False isolation moxibustion combined with false acupuncture
Acupuncture and moxibustion group:Isolated moxibustion combined with acupuncture

Sponsors

Shanghai Seventh People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients with diarrheal IBS who meet the diagnostic criteria; (2) TCM syndrome differentiation belongs to liver depression and spleen deficiency syndrome; (3) Age between 18 and 65 years old gender is not limited; (4) Inspection indicators: the general situation is good; Blood urine stool routine (-) bacterial culture (-) fecal occult blood (-); Liver and kidney function and blood sugar were normal abdominal B was abnormal. Thyroid function was normal. Colonoscopy showed no morphological or histological abnormalities. (5) Sign the patient's informed consent voluntarily.

Exclusion criteria

Exclusion criteria: (1) Patients with organic intestinal lesions; (2) Patients with other types of IBS; (3) Simultaneous use of drugs that affect the efficacy evaluation of this study (such as Smecta desutes Cisapride or traditional Chinese medicine etc.) Of patients; (4) Suffering from other organic diseases of the digestive system tumors confirmed by colonoscopy or barium enema inflammatory bowel disease intestinal tuberculosis or other organic diseases or suffering from systemic diseases causing diarrhea such as lactase deficiency hyperthyroidism etc.; (5) with fever anemia blood in the stool or serious heart liver kidney endocrine and metabolic disorders hematopoietic system disorders malignant tumors or mental disorders and other diseases in the acute stage; (6) Pregnant or lactating women; (7) There are scars or sensory disorders in the body surface area of the acupuncture points involved in this study resulting in the inability to perform acupuncture.

Design outcomes

Primary

MeasureTime frame
Bristol symptom score;

Secondary

MeasureTime frame
Cholesterol 7 a-hydroxylase;Self-Rating Depression Scale (SDS);Irritable Bowel Syndrome Severity Scale (IBS-SSS);Irritable Bowel Syndrome Gastrointestinal Symptom Scale (GSRS-IBS);7 alpha-hydroxy-4-cholesterene-3-one;Self-Rating Anxiety Scale (SAS);Numerical Evaluation Scale for Abdominal Pain (NRS);Total bile acids;Deoxycholic acid;Cholic acid; Effective Response Rate (ERR);IBS Quality of Life Scale (IBS-QOL);TCM syndrome score scale;Intestinal flora;Lithocholic acid;

Countries

People's Republic of China

Contacts

Public ContactYin Shi

Shanghai Seventh People's Hospital

flysy0636@163.com13816042916

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026