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The study of the effect of modified Guishen pill combined with acupuncture on endometrial receptivity anxiety and depression in patients with thin endometrium of kidney deficiency and liver depression

The study of the effect of modified Guishen pill combined with acupuncture on endometrial receptivity anxiety and depression in patients with thin endometrium of kidney deficiency and liver depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000540
Enrollment
Unknown
Registered
2025-03-17
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

self-funded

Interventions

test group:Oral administration of traditional Chinese medicine for tonifying the kidney and soothing the liver
control group:estrogen and progesterone replacement

Sponsors

chengdu women's and children's central hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1) Age: women aged 20 to 40; 2) Infertility patients who meet the diagnostic criteria of thin endometrium and TCM syndrome differentiation of kidney deficiency and liver depression; 3) Have not taken hormone drugs in the past 3 months. 4) The patient's informed consent.

Exclusion criteria

Exclusion criteria: 1) premature ovarian failure Asman syndrome (AS) intrauterine adhesions endometrial tuberculosis etc.; 2) Contraindications to the use of estrogen therapy; 3) Hyperprolactinemia thyroid diseases diabetes and other endocrine diseases; 4) Exclude reproductive system abnormalities (mediastinal uterus unicorn uterus etc.) pelvic organ lesions such as adenomyosis submucosal uterine fibroids endometrial cancer etc.; 5) Those with serious primary diseases such as liver kidney cardiovascular hematopoietic system and severe mental illness;

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate;medium luteal endometrial thickness;Hamilton Anxiety Scale;TCM syndrome integral;Uterine artery blood flow parameters;Pictorial Blood loss Assessment Chart;

Secondary

MeasureTime frame
incidence of LUFS;single follicle ovulation rate;Biochemical pregnancy rate;Early miscarriage rate;

Countries

China

Contacts

Public Contactxianzhi SU

chengdu women's and children's central hospital

suxzhi@163.com15600060796

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026