Knee osteoarthritis
Conditions
Interventions
Patients in the experimental group:Positioning treatment was carried out at the knee acupoint and popliteal fossa acupoint and the needle was left for 30 minutes
Patients in the control group:Non-specific acupuncture points are used to penetrate the skin through pseudo-acupuncture, that is, plastic catheters can be retracted with false needles to open 0.5-5cm
Sponsors
Ningxia Hui Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age 40-70 years old gender is not limited; 2) American College of Anesthesiologists (ASA) classification I.~III.; 3) Diagnosed with osteoarthritis it is planned to undergo primary selective unilateral total knee arthroplasty (TKA) under spinal anaesthesia; 4) There are no contraindications to buccal needle femoral nerve and spinal anaesthesia; 5) No local anaesthetic allergy; 6) Able to cooperate and understand; 7) Obtain informed consent.
Exclusion criteria
Exclusion criteria: 1) Body mass index (BMI) 40; 2) Peripheral neuropathy; 3) severe renal impairment (requiring renal replacement therapy); 4) severe hepatic impairment (Child-Pugh grade C); 5) History of severe cardiovascular disease (NYHA > grade 2); 6) Other circumstances that the attending physician or investigator considers unsuitable to participate in this study; 2.1.1.3 Exclusion criteria: 1) Those who fail to cooperate with the completion of the treatment measures formulated in this study protocol; 2) Those who have not completed the full follow-up of clinical trials; 3) Those who have serious complications or adverse reactions and need to discontinue the experiment as determined by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS pain score at rest and during activity of total knee after TKA ;NRS pain score at rest and during activity at the back of the knee after TKA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee range of motion of patients before and after buccal acupuncture intervention;NRS pain scores of patients before and after buccal acupuncture intervention;Detection of endocannabinoid receptors (CB1R, CB2R, and GPR55) in the synovial membrane of the knee; | — |
Countries
China
Contacts
Public ContactShen Li
Ningxia Hui Autonomous Region People's Hospital
Outcome results
None listed