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The combination treatment of acupuncture & herbal granule for menopausal syndrome of liver-kidney yin deficiency type: the study protocol of efficacy and safety

The combination treatment of acupuncture & herbal granule for menopausal syndrome of liver-kidney yin deficiency type: the study protocol of efficacy and safety

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000532
Enrollment
Unknown
Registered
2025-03-15
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

menopausal syndrome

Interventions

YKY Group:The same dosage of YKY is given to the experimental group for 12 weeks.
YKY + acupuncture Group:Take YKY preparation and acupuncture DU20(Baihui), RN4(Guanyuan), EX-CA1 (Zigong , both sides), SP6 (Sanyinjiao, both sides), LR3 (Taichong, both sides), KI3(Taixi, both sides)

Sponsors

Nanjing Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Women aged 45-60 years old. 2) Meet the diagnostic criteria of liver-kidney yin deficiency type in the Diagnosis and Treatment Guide of integrated Chinese and Western Medicine for menopause syndrome (2023 edition). The main symptoms of this type include: menstrual disorder in menopause more or less menstruation early menstruation bright red color sore waist and knees feverish sensations in palms soles and chest hot sweats dry mouth constipation vaginal dryness red tongue with less coating and wiry pulse. 3) Voluntarily participating in the trial and signing the in-formed consent.

Exclusion criteria

Exclusion criteria: 1)Long-term use of hormones and other chronic disease drugs have an impact on the test results. 2)Participants with serious mental illness or serious mental disorder. 3)Comply with serious heart liver kidney and other functional abnormalities. 4)Participants with gynecological diseases or ovaria-related diseases. 5)Participants with a history of Chinese medicine allergy. 6)Participants who have received Chinese medicine or MHT or HRT (menopausal hormone supplement therapy) in the past two months. 7)Participants have strong resistance to acupuncture and moxibustion. 8)Poor compliance.

Design outcomes

Primary

MeasureTime frame
Kupperman;

Secondary

MeasureTime frame
Blood lipid, sex hormone, HCY, BMI and PSQI, SAS, HAMD ;

Countries

China

Contacts

Public ContactZhan Qun

Nanjing Hospital of Chinese Medicine affiliated to Nanjing University of Chinese Medicine

januaryfirst@163.com18651819939

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026