Pediatric Acute Tonsillitis (syndrome/pattern of heat invading lung and stomach)
Conditions
Interventions
control group 1(Acute suppurative tonsillitis ):Basic treatment (cefuroxime axetil dry suspension)+10% crude dose of Ertong Qingyan Jiere Koufuye
experimental group 2(Acute catarrhal tonsillitis ):Ertong Qingyan Jiere Koufuye
experimental group 1(Acute suppurative tonsillitis ):Basic treatment (cefuroxime axetil dry suspension)+ Ertong Qingyan Jiere Koufuye
control group 2(Acute catarrhal tonsillitis ):10% crude dose of Ertong Qingyan Jiere Koufuye
Sponsors
Beijing Children's Hospital /Capital Medical University
Eligibility
Sex/Gender
All
Age
3 Years to 13 Years
Inclusion criteria
Inclusion criteria: (1) It meets the diagnostic criteria of Western medicine for acute tonsillitis in children; (2) It meets the syndrome differentiation standard of syndrome/pattern of heat invading lung and stomach in traditional Chinese medicine; (3) The age ranged from 3 to 13 years (<14 years); (4) Duration of sore throat = 48h; (5) WBS score of sore throat = 4; (6) Rapid streptococcal antigen (RADT) was negative in children with acute catarrhal tonsillitis; RADT was positive in children with acute suppurative tonsillitis; (7) <8 years old one legal guardian of the child gave informed consent and signed the informed consent form; = At the age of 8 the child and one legal guardian gave informed consent and signed the informed consent form
Exclusion criteria
Exclusion criteria: (1) It is caused by pharyngeal diphtheria scarlet fever Fanshang angina (ulcerative membranous angina) mononucleosis angina agranulocytosis angina and other diseases; (2) Those who have received antibiotics or antiviral treatment before enrollment or have used traditional Chinese medicine with the functions of clearing away heat and toxin reducing swelling and benefiting the throat which has a serious impact on the effectiveness evaluation according to the judgment of the researcher; (3) Those who have difficulty in understanding the WBS pain scale and cannot cooperate with the evaluator; (4) Children with acute otitis media acute sinusitis infectious laryngitis acute bronchitis pneumonia sepsis and other complications; (5) Children with a history of epilepsy or febrile seizures; (6) Patients with severe malnutrition rickets and severe primary diseases of heart brain liver kidney and hematopoietic system; (7) Glucose-6-phosphate dehydrogenase deficiency; (8) Allergic to the test drug and its components; (9) Other circumstances that the investigator considers unsuitable for participating in clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disappearance rate/time of sore throat (days); | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease efficacy (cure rate);Single symptom efficacy (disappearance rate);The curative effect of pharyngeal signs (normalization rate);Severity of sore throat;TCM syndrome curative effect (effective rate);Onset time of sore throat (days);Incidence of complications; | — |
Countries
the People's Republic of China
Contacts
Public ContactXu Baoping
Beijing Children's Hospital /Capital Medical University
Outcome results
None listed