osteoarthritis of the knee
Conditions
Interventions
Observation Group:In the control group, the internal administration of Kidney Regulating Medulla Formula on the basis of hydro-acupuncture knife treatment was carried out One post per day, started at
Control Group:Hydro-acupuncture treatment Hydro-acupuncture treatment is performed once a week, 4 consecutive treatments, 4 weeks as a course of treatment.
Sponsors
Wenzhou Integrated Traditional Chinese and Western Medicine Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: The diagnostic criteria Refer to the Chinese Medicine Treatment Guidelines for Osteoarthritis of the Knee (2020 edition) for western medical diagnosis: 1) recurrent knee pain in the past month; 2) age =50 years; 3) morning stiffness =30 min; 4) bone friction sound (sensation) during activity; 5) X-ray (standing or weight-bearing position) shows narrowing of joint space subchondral bone sclerosis and/or cystic degeneration and formation of bone capillaries at the joint margins. X-ray (standing or weight-bearing position) shows narrowing of the joint space subchondral bone sclerosis and/or cystic degeneration and formation of bone capillaries at the joint margin. The diagnosis can be made if any two of 1) and 2) 3) 4) 5) are met. X-ray grading: refer to the Kellgren-Lawrence grading method: 1) grade 0 no change (normal); 2) grade ? suspected bony encumbrance normal joint space; 3) grade ? definite bony encumbrance suspected narrowing of the joint space; 4) grade ? moderate amount of bony encumbrance definite narrowing of the joint space sclerosis; 5) grade ? large amount of bony encumbrance definite narrowing of the joint space severe sclerosis. 5) Grade IV Large amount of bony redundancy clear narrowing of joint space serious sclerosis. Diagnosis in TCM: KOA: Liver and kidney deficiency type (primary symptom: vague pain in the joints. secondary symptom: lumbar and knee pain and weakness). Secondary symptoms: lumbar and knee weakness soreness and pain worse with exertion. Tongue and pulse: red tongue with little moss; pulse is thin and weak). Inclusion Criteria All included patients met the following three points: 1) met the above KOA western medical diagnosis and Chinese medical diagnosis; 2) X-ray grading of grade II-III and 3) those who agreed to enroll in this experiment and signed the corresponding formula.
Exclusion criteria
Exclusion criteria: 1) Those who belong to the liver and kidney deficiency type of KOA but with the presence of co-morbidities affecting the joints; 2) Patients with combined cardiovascular cerebrovascular hepatic renal hematopoietic endocrine system and other serious primary diseases and psychiatric disorders; 3) Those whose condition is critical making it difficult to make a definitive evaluation of the effectiveness and safety of the treatment modality; 4) Those who have had previous needle-sickness or blood-sickness; 5) Those who have already received other related treatments that may affect the observation of the effect indexes of the present study; 5) Patients with trauma surgery or any history of invasive surgery of the affected joints within the past 6 months or poor alignment of the lower limbs; 6) Patients with clear contraindications to hydroentanglement therapy or previous history of hydroentanglement therapy; 7) Allergy and the presence of allergies to a variety of drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prognostic comparison; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Arthritis Index,(WOMAC);Visual analog score (VAS score);Indicators of inflammatory factors:(tumor necrosis factor a,TNF-a)(interleukin 1,IL-1ß)-6(interleukin 1,IL-6); | — |
Countries
China
Contacts
Public ContactXiaofeng Wang
Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Zhejiang Chinese Medical University
Outcome results
None listed