allergic rhinitis
Conditions
Interventions
experimental group:Yiqingyangfang granules orally 1 dose each time 2 times a day. Total 28 doses
Non-AR group:Without any drug intervention, only 15 ml of venous blood was taken at the time of enrollment.
control group:Loratadine tablet, orally, 1 tablet once a day. Total 28 doses
Sponsors
jiangsu province hospital of chinese medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Experimental group : 1.Patients who meet the diagnostic criteria of allergic rhinitis and the syndrome differentiation criteria of lung spleen deficiency and cold syndrome in traditional Chinese medicine. 2.Age between 18 to 65 years old gender is not limited. 3.There was no history of asthma attack and other allergic diseases within 6 months before enrollment ; 4.No glucocorticoids were used within 1 week before enrollment and no anti-allergic drugs such as H1 antihistamines and leukotriene receptor antagonists were used within 1 week ; 5.Informed consent voluntary subjects. The process of obtaining informed consent should be in accordance with GCP regulations. Non-AR group : 1.Patients who do not meet the Western diagnostic criteria for allergic rhinitis ; no disease with similar clinical symptoms to allergic rhinitis such as acute rhinitis vasomotor rhinitis non-allergic rhinitis with eosinophilia syndrome ; 2.Age between 18 to 65 years old ( including 18 years old and 65 years old patients ) ; 3.There was no history of asthma attack and other allergic diseases within 6 months before enrollment ; 4.Patients who are not in a state of pregnancy ( suspected pregnancy may or within 3 weeks of sexual behavior without effective contraception before the group blood HCG examination ). 5.Informed consent voluntary subjects ( the process of obtaining informed consent should be in accordance with GCP regulations ).
Exclusion criteria
Exclusion criteria: xperimental group : 1.Patients who do not meet the Western diagnostic criteria for allergic rhinitis ; acute rhinitis vasomotor rhinitis non-allergic rhinitis with eosinophilia syndrome ( diseases with similar clinical symptoms to allergic rhinitis ) ; 2.TCM syndrome differentiation does not meet the standard of lung spleen deficiency and cold syndrome or has obvious accompanying syndrome ; 3.Other Chinese and Western medicines for the treatment of allergic rhinitis have been used after the onset of this disease. 4.Pregnancy lactation women. 5.Severe primary heart liver lung kidney blood or serious diseases affecting their survival such as coronary heart disease. 6.Because of intellectual or behavioral disorders can not give full informed consent. 7.Suspected or had a history of alcohol and drug abuse. 8.According to the judgment of the researcher other lesions that reduce the possibility of enrollment or complicate the enrollment such as frequent changes in the working environment are likely to cause loss of follow-up. 9.Allergic constitution such as two or more drugs or food allergy history ; or known to be allergic to the ingredients of this drug. 10.Patients who are participating in clinical trials of other drugs. Non-AR group : 1.Patients with allergic rhinitis previous history of asthma attacks and other history of allergic diseases ; have a disease with similar clinical symptoms to allergic rhinitis. 2.Pregnancy lactation women. 3.Severe autoimmune diseases metabolic diseases primary heart liver lung kidney blood or serious diseases affecting their survival. 4.Because of intellectual or behavioral disorders can not give full informed consent. 5.suspected or had a history of alcohol and drug abuse. 6.According to the judgment of the researchers other lesions that reduce the possibility of enrollment or complicate the enrollment such as frequent changes in the working environment are likely to cause loss of follow-up. 7. Patients who are participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal itching;Nasal mucosa situation;runny nose;sneezing; | — |
Secondary
| Measure | Time frame |
|---|---|
| fatigue;spontaneous perspiration;tongue coating;Cold;tongue;pulse; | — |
Countries
China
Contacts
Public ContactJun Shi
jiangsu province hospital of chinese medicine
Outcome results
None listed