Coronary heart disease with heart failure
Conditions
Interventions
Treatment group:Qiyi granules formula + conventional treatment of Western medicine
Sponsors
Jiangsu Province Hosptial of Chinese Medicine Affiliated Hosptial of Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Those who meet the diagnosis of coronary heart disease NYHA cardiac function classification: grade II-III LVEF <50% measured by echocardiography and blood BNP/NT-proBNP elevation meets the standard. 2. It is in line with the syndrome type of qi and yin deficiency and phlegm stasis and paralysis in traditional Chinese medicine. 3. Age between 18~80 years old gender is not limited. 4. Informed consent voluntary test. The process of obtaining informed consent should be in accordance with GCP regulations.
Exclusion criteria
Exclusion criteria: 1. Combined with severe heart valve disease and myocarditis. 2. Combined with malignant tumors connective tissue diseases rheumatic immune system diseases and hematologic diseases. 3. Asthma chronic obstructive pulmonary disease and severe acute and chronic infectious diseases. 4. Patients with severe liver and kidney insufficiency. 5. Pregnant or lactating females. 6. Uncontrollable mental illness. 7. Those with unclear ultrasound images. 8. Suspected or confirmed history of alcohol and drug abuse. 9. According to the judgment of the investigator there are other pathologies that reduce the possibility of enrollment or complicate enrollment such as frequent changes in the working environment and other conditions that are easy to cause loss to follow-up. 10. Allergies such as a history of allergies to two or more drugs or food; or those who are known to be allergic to the ingredients of this medicine. 11. Patients who are participating in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Routine echocardiography;Analysis of 2D speckle tracking imaging techniques;Brain Natriuretic Peptide; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM symptom efficacy indicators; | — |
Countries
China
Contacts
Public ContactLingzhun Wang
Jiangsu Province Hosptial of Chinese Medicine Affiliated Hosptial of Nanjing University of Chinese Medicine
Outcome results
None listed