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Effects of acupoint injection of different drugs at Zusanli on postoperative nausea and vomiting after gynecological laparoscopic surgery

Effects of acupoint injection of different drugs at Zusanli on postoperative nausea and vomiting after gynecological laparoscopic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000485
Enrollment
Unknown
Registered
2025-03-07
Start date
2024-09-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

Group D:After anesthesia induction vitamin B11.0mL 50mg and dexamethasone 1.0mL 5mg were injected into bilateral Zusanli acupoints
Group A:After anesthesia induction 2.0mL normal saline was injected into bilateral Zusanli acupoints
Group C:After anesthesia induction normal saline 1.0mL+ dexamethasone 1.0mL 5mg was injected into bilateral Zusanli acupoints
Group B:After anesthesia induction normal saline 1.0mL+ vitamin B1 1.0mL 50mg was injected into bilateral Zusanli acupoints

Sponsors

Department of Anesthesiology, Yijishan Hospital, Wannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years old; 2. Female patients of American Society of Anesthesiologists physical status ? or ?; 3. Never smoked; 4. General anesthesia; 5. Laparoscopic surgery; 6. The preoperative physical examination and laboratory examination were basically normal. 7. Good mental state and good compliance

Exclusion criteria

Exclusion criteria: 1. Patients with uncontrolled hypertension diabetes coronary heart disease and other chronic diseases or severe organ dysfunction; 2. History of mental illness or long-term use of psychotropic drugs; 3. Patients with puncture site damage or infection; 4. Long-term use of glucocorticoids or allergic to them; 5. Patients with abnormal lung liver kidney function and coagulation function before operation; 6. Patients with recent use of sedatives or antiemetics

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative nausea and vomiting;

Secondary

MeasureTime frame
Time to first bowel movement;Use of additional antiemetic medications;visual analogue scale for pain(VAS);The time of first anal exsufflation;Gastrointestinal Symptom Rating Scale(GSRS);Incidence and severity of postoperative nausea and vomiting;Postoperative Quality of Recovery Score(Qor-15);

Countries

China

Contacts

Public ContactMeijing Lu

Department of Anesthesiology, Yijishan Hospital, Wannan Medical College

619466076@qq.com+86 139 5536 7332

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026