Unstable Angina Pectoris of Coronary Heart Disease
Conditions
Interventions
Standard Intensive Western Medical Therapy Group:Standard Intensive Western Medical Therapy, with a conventional treatment regimen including: Anti-myocardial ischemia therapy,Antiplatelet aggregation
Treatment Group:Ningxin Yin Herbal Formula
Sponsors
Nan Jing Hospital of C.M.
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for coronary atherosclerotic heart disease in Western medicine. Coronary angiography (CAG) or coronary computed tomography angiography (CTA) reveals at least one epicardial coronary artery with a diameter stenosis exceeding 50%; or a clear history of myocardial infarction with resting electrocardiogram (ECG) showing evidence of a past myocardial infarction; or a history of revascularization [percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)]. 2.Meet the diagnostic criteria for unstable angina pectoris in Western medicine (including new-onset exertional angina worsening angina or spontaneous angina) classified as intermediate or low risk. 3.Meet the diagnostic criteria for the traditional Chinese medicine (TCM) syndrome of "chest obstruction and heart pain" (). 4.Meet the TCM syndrome diagnostic criteria for "phlegm-stasis obstruction syndrome" () as defined in this research study. 5.Age =18 and =75 years old; gender is not restricted. 6.Patients who do not currently plan to undergo revascularization (PCI or CABG). 7.Patients voluntarily agree to participate in this clinical study and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients confirmed by examination to have acute myocardial infarction due to coronary heart disease unstable angina with high-risk stratification or chest pain caused by other cardiac conditions cardiac neurosis menopausal syndrome or cervical spondylosis. 2.Patients with severe cardiopulmonary insufficiency severe arrhythmias severe primary diseases of the liver kidneys or hematopoietic system or psychiatric disorders. 3.Pregnant or breastfeeding women. 4.Patients with a known allergy to the study medication. 5.Patients who are planning to immediately undergo revascularization (PCI or CABG).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Serum TC, LDL-C, and TG Levels;Change in the Reduction or Discontinuation Rate of Sublingual Nitroglycerin Tablets; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in TCM Syndrome Scores and Therapeutic Efficacy;The study evaluated the therapeutic efficacy of TCM "chest obstruction" symptoms, including the frequency, severity, duration, triggers, and changes in accompanying symptoms of angina pectoris.;Liver Function Tests, Renal Function Tests, Blood Glucose, and Routine Blood, Urine, and Stool Tests;Changes in ECG Results;Change in cTnI Levels ; | — |
Countries
China
Contacts
Public ContactHuang Xia
Nan Jing Hospital of C.M.
Outcome results
None listed