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Multomic Differences Between Phlegm-Dampness Type PCOS (PCOS-IR) and Non-Phlegm-Dampness Type PCOS (PCOS-NIR)

Multomic Differences Between Phlegm-Dampness Type PCOS (PCOS-IR) and Non-Phlegm-Dampness Type PCOS (PCOS-NIR)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000481
Enrollment
Unknown
Registered
2025-03-06
Start date
2024-12-09
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Syndrome

Interventions

Non-Phlegm-Dampness Type PCOS-NIR:Collect and Store Blood Samples
Healthy population:Collect and Store Blood Samples
Phlegm-Dampness Type PCOS-IR:Collect and Store Blood Samples

Sponsors

The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion Criteria for Phlegm-Dampness Type PCOS-IR (1) Age between 18 and 45 years old; (2) Meet the diagnostic criteria for PCOS-IR in Western medicine and also meet the criteria for phlegm-dampness syndrome in Traditional Chinese Medicine (TCM); (3) Have not taken any medications that affect sex hormones within the past three months; (4) Willing to sign the informed consent form. 2. Inclusion Criteria for Non-Phlegm-Dampness Type PCOS-NIR (1) Age between 18 and 45 years old; (2) Meet the diagnostic criteria for PCOS-IR in Western medicine but do not meet the criteria for phlegm-dampness syndrome in Traditional Chinese Medicine (TCM); (3) Have not taken any medications that affect sex hormones within the past three months; (4) Willing to sign the informed consent form. 3. Inclusion Criteria for Control Group (1) Age between 18 and 45 years old; (2) Confirmed through health check-ups to have no severe organic or functional diseases; (3) Do not have PCOS or IR; (4) Willing to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Other diseases that cause ovulatory dysfunction (including thyroid dysfunction premature ovarian failure hypothalamic-pituitary amenorrhea hyperprolactinemia etc.) and diseases that cause hyperandrogenemia (including Cushing's syndrome non-classic congenital adrenal hyperplasia androgen-secreting endocrine tumors etc.); (2) Patients with severe cardiovascular and cerebrovascular diseases liver kidney or hematopoietic system diseases malignancies or psychiatric disorders; (3) Those who have taken hormonal medications (except progesterone) or metformin within the past three months that may affect the results; (4) Individuals currently participating in other clinical studies or planning to become pregnant within the next three months. Any individual meeting one or more of the above criteria will be excluded.

Design outcomes

Primary

MeasureTime frame
Differentially Expressed Proteins;

Countries

China

Contacts

Public ContactWei Chen

The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

chenwei8027@163.com18698807121

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026