disturbance of consciousness
Conditions
Interventions
Hyperbaric oxygen group:hyperbaric oxygen therapy
Ear acupressure needle group:Ear acupressure and hyperbaric oxygen therapy
Electroacupuncture group:Electroacupuncture and hyperbaric oxygen therapy
Sponsors
The First Affiliated Hospital of Guangdong Pharmaceutical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for ischemic or hemorrhagic stroke; (2) Meeting the diagnostic criteria for minimal conscious state and vegetative state among consciousness disorders, and being assessed as minimal conscious state and vegetative state according to CRS-R; (3) Age over 18 years and under 90 years, regardless of gender; (4) Disease duration from 2 weeks to 12 months; (5) The sole cause of consciousness disorder is brain injury; (6) The patient's guardian has filled out the informed consent form and agreed to participate in this clinical research subject. Only those who meet all the above conditions can be included.
Exclusion criteria
Exclusion criteria: (1) Patients with new, recurrent, or progressive stroke, or those with a disease course of less than 2 weeks; (2) Patients with unstable conditions (including status epilepticus, increased intracranial pressure, heart failure, respiratory failure, shock, hypertensive crisis, etc.); (3) Patients with clear neurodevelopmental disorders before the onset of consciousness disorders; (4) Patients with special infections (such as tuberculosis, H1N1 influenza, COVID-19, avian influenza, other atypical pneumonias, etc.) and those using mechanical ventilation; (5) Patients with contraindications for acupuncture, including skin damage, infection, severe bleeding tendency, allergic reactions, etc., at the acupuncture site, and those with contraindications for hyperbaric oxygen therapy; (6) Patients participating in other research studies simultaneously; (7) Patients who are unable to cooperate; or those deemed unsuitable for participation in this study by the researcher due to complications or other reasons. Any patient meeting one of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brainstem auditory evoked potential (BAEP);Electroencephalogram (EGG);Revised Coma Recovery Scale (CRS-R); | — |
Secondary
| Measure | Time frame |
|---|---|
| Cerebrovascular Color Doppler Ultrasound (TCD);National Institutes of Health Stroke Scale (NIHSS); | — |
Countries
China
Contacts
Public Contactxing bing feng
The First Affiliated Hospital of Guangdong Pharmaceutical University
Outcome results
None listed