multiple myeloma
Conditions
Interventions
Integrated Traditional Chinese and Western Medicine Treatment Group:Basic supportive treatment plus primary disease treatment plus kidney tonifying phlegm resolving and blood stasis removing therapy
Western medicine control group:Basic supportive treatment plus primary disease treatment
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the Western diagnostic criteria for multiple myeloma; 2. Meet the traditional Chinese medicine standards for multiple myeloma with kidney deficiency and phlegm stasis syndrome; 3. Age = 18 years old and = 80 years old gender not limited; 4. Willing to accept this treatment plan and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with allergic constitution or allergies to relevant MM treatment drugs; 2. Severe heart disease including myocardial infarction and heart failure grade 3 or above; 3. Patients with severe liver and kidney dysfunction (ALT>5 * ULN GRF<15ml/min); 4. Other systemic diseases with clinical significance such as osteoporosis bone metastases and lumbar tuberculosis; 5. Patients with two or more complications such as bone disease infection bleeding anemia etc; 6. Individuals with alcoholism drug abuse mental disorders and intellectual disabilities; 7. Pregnant or lactating women..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number and proportion of T cell subpopulations;Number and proportion of NK cell subpopulations;NK cell activation and killing function;CD3+T cells;Immune checkpoint and T cell depletion molecules; | — |
Secondary
| Measure | Time frame |
|---|---|
| Whole blood cell count+C-reactive protein;Hematuria immunoglobulin M protein quantification free light chain ß 2-microglobulin;Whole body X-ray plain film or CT or MRI or PET CT;Western medicine efficacy evaluation;Safety indicators;Symptoms and signs;Quantitative integration of traditional Chinese medicine syndromes;Bone marrow examination; | — |
Countries
China
Contacts
Public Contacthailin chen
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Outcome results
None listed