Cough-variant asthma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects who meet all 4 of the following may be included in the study: 1) Meet the diagnostic criteria for CVA; 2) Age 18-60 years old gender is not limited right-handed; 3) Regular application of antiasthmatic therapeutic drugs (mainly bronchodilators and [or] glucocorticoids) for at least 4 weeks without complete symptomatic relief with a cough severity VAS score value of >30 mm; 4) Voluntarily participate in this trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: Patients meeting any 1 of the following were excluded: 1) People who have a history of acute respiratory infections or are experiencing acute respiratory infections in the last 2 weeks such as colds pneumonia active tuberculosis; 2) Combined typical asthma COPD and other respiratory diseases that have symptoms such as shortness of breath in addition to coughing as the main complaint; 3) Cancer mental illness cognitive dysfunction and hearing impairment that prevents normal communication; 4) Acupuncture local skin lesions such as burns eczema ulcers frostbite ulceration or coagulation disorders; 5) Women who are breastfeeding pregnant or preparing for pregnancy; 6) Patients within the last six months or who are participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Leicester cough questionnaire;Cough evaluation test;Coughing frequency in 24h;Fractional exhaled nitric oxide;Pittsburgh sleep quality index;Hamilton anxiety scale;Cough severity dairy;Cough hypersensitivity questionnaire;Hamilton depression scale;Peripheral blood eosinophil counts; | — |
Countries
the People's Republic of China
Contacts
Hospital of Chengdu University of Traditional Chinese Medicine