Perianal Abscess
Conditions
Interventions
Antibiotics group:Oral administration of Cefdinir for 5 days, 0.1g per dose, 3 times a day.
TCM group:Oral administration of Qinghua Xiaoyong Formula for 2 weeks twice a day 1 packet per dose.
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with perianal abscess who meet the above diagnostic criteria; 2. Aged 18 to 70 years regardless of gender; 3. Willing to undergo incision and drainage surgery; 4. Perianal abscess with an abscess cavity size between 4 cm³ and 32 cm³ and the deepest part not exceeding 5 cm above the anal margin excluding horseshoe-shaped abscesses; 5. Willing to receive oral traditional Chinese medicine treatment; 6. Voluntarily participate in this trial and sign an "Informed Consent Form."
Exclusion criteria
Exclusion criteria: 1. Allergic to cephalosporin antibiotics or related traditional Chinese medicines; 2. Used any antibiotics within one week prior to inclusion; 3. Suffering from infections at other sites during the treatment period; 4. A history of anal and rectal surgery; 5. Diagnosed with diabetes inflammatory bowel disease tuberculosis HIV/AIDS immunodeficiencies or other conditions that affect wound healing; 6. Pregnant or breastfeeding women; 7. Suffering from mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction rate of inflammatory infiltration area; | — |
Secondary
| Measure | Time frame |
|---|---|
| stool characteristics and frequency;fever;IL-6;IL-1ß;CRP;Gut Microbiota;Fistula formation status;ESR;TNF-a;Wound healing time;White Blood Cell Count;Neutrophil Count;IL-8;quality of life score;wound exudate score;PCT;pain; | — |
Countries
China
Contacts
Public ContactFang Chenyang
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed