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The effect of Wenshen Huatan Formula on pregnancy rate and androgen metabolism in infertile patients with polycystic ovary syndrome of kidney deficiency and phlegm dampness syndrome

The effect of Wenshen Huatan Formula on pregnancy rate and androgen metabolism in infertile patients with polycystic ovary syndrome of kidney deficiency and phlegm dampness syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000410
Enrollment
Unknown
Registered
2025-02-25
Start date
2023-11-14
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

Test group:conbined treatment of traditional chinese medicine and western medicine
control group:Comparison with Western Medicine Treatment

Sponsors

Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Those who meet the above traditional Chinese medicine syndrome differentiation and Western medicine diagnostic criteria. (2) Patients with combined hyperandrogenism (elevated levels of testosterone, free testosterone, androstenedione, and dehydroepiandrosterone sulfate can be included). (3) Individuals between the ages of 18 and 40 (including 18 and 40) who have a desire to have children. (4) Patients who are willing to accept experimental and control measures, sign informed consent forms, and are eligible for follow-up.

Exclusion criteria

Exclusion criteria: (1) Those who have been ineffective in using trastuzumab to induce ovulation in the past. (2) Menstrual disorders caused by organic lesions of the reproductive organs (such as uterine fibroids, adenomyosis, pituitary tumors, etc.) after examination. (3) Suffering from adrenal hyperplasia syndrome, thyroid disease, or tumors, etc; Functional uterine bleeding; Primary diabetes and endocrine disorders; There are other causes of hyperandrogenism. (4) Patients with primary diseases such as liver and kidney, cardiovascular, cerebrovascular, and hematopoietic systems, as well as psychiatric disorders. (5) Allergic constitution, such as a history of allergies to two or more drugs or foods; Or those who are allergic to known ingredients of this medicine. (6) Patients who are currently participating in clinical trials of other drugs. (7) Those who cannot cooperate with treatment and cannot be followed up.

Design outcomes

Primary

MeasureTime frame
testosterone;Pregnancy rate;

Secondary

MeasureTime frame
ovulation rate;HOMA-IR;Traditional Chinese Medicine Syndrome Score;

Countries

China

Contacts

Public ContactXin Mingwei

Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University

1355286676@163.com13552866767

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026