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A Double Blind Randomized Controlled Study on the Prevention of Early Pregnancy loss in Patients with Recurrent Pregnancy Loss after PGT-A with Zishen Yutai Pill

A Double Blind Randomized Controlled Study on the Prevention of Early Pregnancy loss in Patients with Recurrent Pregnancy Loss after PGT-A with Zishen Yutai Wan

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000400
Enrollment
Unknown
Registered
2025-02-24
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rcurrent pregnancy loss

Interventions

ZS Group:Zishen Yutai Pill
Placebo group:Placebo

Sponsors

the First Affliated Hospital Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: The age of the woman is 20-40 years old; They met the RPL diagnostic criteria and had two or more early embryo loss histories before 13 weeks of gestation; Regular menstrual cycle 22-35 days; PGT-a oocyte retrieval cycle has been completed and at least one transplantable euploid blastocyst has been obtained; Qualified and willing to carry out long-term follow-up;

Exclusion criteria

Exclusion criteria: Moderate intrauterine adhesions and untreated endometrial polyps; Moderate to severe adenomyosis; Diagnosed endocrine diseases: diabetes untreated thyroid dysfunction; Autoimmune diseases: diagnosed connective tissue diseases antiphospholipid syndrome; I have a history of thrombosis or a family history of thrombosis; Other clear contraindications of pregnancy; Allergic to Zishen Yutai pills or intolerant to its side effects;

Design outcomes

Primary

MeasureTime frame
Early pregnancy loss;

Secondary

MeasureTime frame
Ongoing pregnancy;Pregnancy complication;Adverse drug reaction;Clinical pregnancy;

Countries

China

Contacts

Public ContactLu Luo

the First Affliated Hospital Sun Yat-sen Universityi

gzluolu@qq.com13711264464

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026