Children's Myopia and Ocular Surface Health
Conditions
Interventions
Research Group (Ocular Surface Research Section):intradermal needle therapy + orthokeratology
Control group (ocular surface study portion):Orthokeratology
Research Group (Enhanced Efficacy Study Section):intradermal needle therapy + orthokeratology
Control group (enhanced efficacy study part):Orthokeratology
Sponsors
Eye & Ent Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
8 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Corneal Research Section (1) Trial wear of orthokeratology lenses is successful, i.e., subjects who will wear orthokeratology lenses regularly; (2) Age between 8-12 years old; (3) Refractive error after cycloplegia: -4.00 D to -0.50 D, astigmatism =1.50 D, anisometropia =1.50 D, corrected visual acuity =0.8, intraocular pressure between 10-21 mmHg; (4) Patients voluntarily join the trial with good compliance, and both the subject and guardian have signed the informed consent form. 2. Enhancement Study Section (1) Regular wear of orthokeratology lenses for more than 3 months; (2) Age between 8-12 years old; (3) Refractive error after cycloplegia: -4.00 D to -0.50 D, astigmatism =1.50 D, anisometropia =1.50 D, corrected visual acuity =0.8, intraocular pressure between 10-21 mmHg; (4) Voluntarily join the study with good compliance, and the guardian has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Ocular Surface Research Section (1) Patients with other ocular diseases (cataracts, congenital retinal diseases, strabismus, amblyopia, etc.) or systemic diseases; (2) Patients with active ocular lesions or a history of ocular surgery; (3) Patients unable to cooperate with ocular examinations or treatments; (4) Patients with local acupoint skin damage or inflammation; (5) Patients who have worn orthokeratology lenses; (6) Patients who have used any myopia control methods within the past month; (7) Patients with adhesive or metal allergies. 2. Efficacy Enhancement Research Section (1) Patients with other ocular diseases (cataracts, congenital retinal diseases, strabismus, amblyopia, etc.) or systemic diseases; (2) Patients with active ocular lesions or a history of ocular surgery; (3) Patients unable to cooperate with ocular examinations or treatments; (4) Patients with local acupoint skin damage or inflammation; (5) Patients who have used any myopia control methods (excluding orthokeratology lenses) within the past month; (6) Patients with adhesive or metal allergies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index;Change in axial length of the eye; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success time of orthokeratology lens wearing and removal;Non-invasive break-up time;Tear meniscus height;Red eye index;Corneal fluorescein staining;Hospital Anxietyand Depression Scale;Equivalent Sphere;corneal curvature;Anterior chamber depth; | — |
Countries
China
Contacts
Public ContactXingtao Zhou
Eye & ENT Hospital of Fudan University
Outcome results
None listed