AIDS Immunological Non-responder
Conditions
Interventions
treatment group:ART + Qushi Jiedu Granules
control group:ART
Sponsors
Research on Basic Theory of Traditional Chinese Medicine in China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1 ) Age 18-65 years old men and women are not limited ; 2 ) HIV antibody positive confirmed by Western Blot confirmation test ; 3 ) The duration of ART treatment was more than 4 years and the plasma HIV load < 50copies / ml was more than 3 years ; 4 ) CD4 + T lymphocyte count less than 350 cells / ul ; 5 ) TCM syndrome differentiation in line with damp-heat syndrome ; 6 ) Voluntary to participate in this study signed informed consent.
Exclusion criteria
Exclusion criteria: 1)severe opportunistic infections were not controlled before enrollment ; 2)Patients within 1 month before enrollment or participating in clinical trials of other drugs ; 3)Patients who received immunomodulator therapy within 1 month before enrollment ; 4)WBC < 2 × 109 / L N < 1.0 × 109 / L Hb < 90g / L PLT < 75 × 109 / L abnormal liver and kidney function ( abnormal liver function refers to AST or ALT or T-BIL = 2 times the upper limit of reference value abnormal renal function refers to creatinine clearance rate lower than normal ). 5)pregnant or lactating women or women preparing for pregnancy ; 6)combined with other serious diseases ( such as tumors cirrhosis cardiovascular and cerebrovascular diseases etc. ) ; 7)Patients with intellectual or language barriers who could not fully understand the content of the trial or give good cooperation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| immunologic index; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical symptoms;inflammation-related indicators;WHOQOL-HIV BREF; | — |
Countries
China
Contacts
Public Contactliuying
Institute of Basic Theory of Chinese Medicine China Academy of Chinese Medical Sciences
Outcome results
None listed