post-stroke depression
Conditions
Interventions
treatment group:Acupuncture combined with oral administration of sertraline
Sponsors
Chengdu First People's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 75 Years
Inclusion criteria
Inclusion criteria: 1) Meets the diagnostic criteria for post-stroke depression with a HAMD-17 score ranging from 8 to 24 points; 2) The patient is conscious with stable vital signs and able to cooperate with examination and treatment; 3) Age<75 years old; 4) Disease duration<3 months; 5) Have not received acupuncture treatment or taken antidepressants in the 30 days prior to the study; 6) Not participating in other ongoing clinical studies; 7) Sign the informed consent form and voluntarily participate in this study. Note: Only subjects who meet all 7 criteria mentioned above can be included in this study
Exclusion criteria
Exclusion criteria: 1) Individuals with a history of mental illness or family history of mental illness; 2) Individuals with a history of depression prior to the occurrence of stroke; 3) Individuals with cognitive impairments articulation disorders aphasia hearing impairments etc. who cannot cooperate; 4) Those who cannot tolerate acupuncture or cannot cooperate in completing this experiment Note: Participants who meet any of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Levels of GABA DA NE Glu Ach and 5-HT in encephalofluctuograph; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional independence measure;Hamilton Depression Scale;Montgomery-Åsberg Depression Rating Scale;Treatment Emergent Symptom Scale;National Institute of Health stroke scale; | — |
Countries
China
Contacts
Public ContactMing Liu
Chengdu First People's Hospital
Outcome results
None listed