Unexplained Recurrent Spontaneous Abortion
Conditions
Interventions
SiShenWan:The medical record shows that during this pregnancy the patient received SishenWan (continuously taken for = 2 weeks) which can be combined with routine Western medicine treatment for fetal
Control:Patients who did not receive Sishen Pill treatment
Sponsors
The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of unexplained recurrent miscarriage (URSA): natural miscarriage = 2 or = 3 times excluding known causes such as immunity genetics anatomy endocrinology and infection; 2. Age between 18 and 45 years old with complete outpatient or inpatient medical records available for review; 3. Have received fetal protection treatment in our hospital and have clear records of whether to use the "Si Shen Wan"; 4. The pregnancy outcome data in the medical record is complete and can be traced back to pregnancy up to 12 weeks and above or perinatal outcomes.
Exclusion criteria
Exclusion criteria: 1. Discovering obvious causes or serious organic diseases (tumors severe liver liver and kidney dysfunction etc.); 2. The data is severely missing making it impossible to confirm the pregnancy outcome or medication use; 3. During pregnancy other traditional Chinese medicine formulas were used but it was not possible to distinguish whether they included Si Shen Wan; 4. The combination of other special medications during pregnancy may significantly affect the results (such as high-dose hormones immunosuppressants etc.) and the effects cannot be distinguished.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful pregnancy rate;Live birth rate (the proportion of live infants delivered at or near full term); | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrent miscarriage rate (miscarriage situation at this time or follow-up);Pregnancy complications (pregnancy hypertension diabetes etc.);Newborn condition (birth weight Apgar score if recorded); | — |
Countries
China
Contacts
Public ContactZhouXuan
The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
Outcome results
None listed