Schizophrenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.According to the diagnostic criteria of SCZ in the 10th edition of the International Classification of Diseases (ICD-100) patients were diagnosed as SCZ by psychiatrists 2. Age >=18 years old. 3.Receiving routine psychiatric treatment and management during the hospital maintenance period and receiving antipsychotic drugs during the continuous hospitalization for more than 1 year. 4.I can cooperate with the investigation smoothly. I and my family members agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Unable to cooperate with the investigators due to the change of the patient's condition and great mood fluctuations during the study; 2.Affected lumbar spine and femoral neck bone mineral density by DXA evaluation; 3.Complicated with severe endocrine diseases; 4.Substance or alcohol dependent patients; 5.Pregnant and lactating women; 6.Those who cannot cooperate with the study or withdraw from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone metabolism index;Blood routine index;visual analogue scale;IOF Osteoporosis Risk Test Sheet;Targeting metabolomics;FRAX;Calcium and phosphorus metabolism index;Metagenomic sequencing;Physical examination index;Positive and negative symptom scale; | — |
Countries
China
Contacts
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine