chronic kidney disease
Conditions
Interventions
test group:Basic therapy and Bushen Tiaozhong granules
control groups:Basic therapy and Bushen Tiaozhong decoction placebo
Sponsors
Xiyuan Hospital of CACMS
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Western medicine diagnosis of chronic kidney disease stage 4-5 and no dialysis; (2) Chinese medicine diagnosis is consistent with spleen deficiency and dampness obstruction; (3) Age 18-75 years old gender is not limited; (4) 24h urine protein quantification = 2.0g; (5) Voluntarily accept this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: rmal reference value) and clinically significant ECG abnormalities. (4) Hypersensitivity to the study drug and allergy; (5) Pregnant and lactating women; (6) Participants in other clinical trials within the last 1 month; (7) Mental or cognitive disorders that prevent subjects from understanding the trial instructions providing informed consent as well as those who are unable to take the medication on time have poor compliance or are unable to adhere to follow-up visits. If the patient is a woman of childbearing age it is necessary to ask carefully whether there is a possibility of pregnancy to ensure that the enrolled patients meet the inclusion and exclusion criteria and to emphasize the need for strict contraceptive measures during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Creatinine ;Estimated Glomerular Filtration Rate;Traditional Chinese Medicine Syndrome Scoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cholesterol;T4/T8;Total T and B Cell Count;Serum Albumin; | — |
Countries
China
Contacts
Public ContactYu Dajun
Xiyuan Hospital of CACMS
Outcome results
None listed