Premature Ovarian insufficiency
Conditions
Interventions
Control group: Sham acupuncture + Western medicine "Fenmuto"
Experimental group:Acupuncture + Western medicine "Fenmuto"
Sponsors
Hubei University of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) Women with POI aged between 20 and 40 years old; 2) Those who are willing to receive acupuncture treatment; 3) Those who have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Those with congenital reproductive organ developmental abnormalities organic lesions such as ovarian tumors or those with decreased ovarian function due to radiotherapy and chemotherapy etc; 2) Those with secondary amenorrhea caused by polycystic ovary syndrome hyperprolactinemia thyroid diseases etc; 3) Those with severe primary diseases such as heart liver kidney and hematopoietic system diseases; 4) Those with mental disorders who are unable to cooperate with treatment; 5) Those who have received acupuncture or sex hormone treatment within the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Estradiol;menstrual reting scale;Resistance Index;Interleukin-10;Peak Systolic Velocity;Anti-Müllerian hormone;luteinizing hormone;Interferon-?;Regulatory T cells;Tumor necrosis factor-a;Self-rating anxiety scale;Antral follicle count;Transforming growth factor-beta;Safety Observation Indicators (blood routine, urine routine, liver and kidney function, adverse event records);Pittsburgh sleep quality index;Helper T cells;Follicle-stimulating hormone;pulsatility index; | — |
Countries
China
Contacts
Public ContactWAN Xiaoman
Hubei University of Chinese Medicine
Outcome results
None listed